3-(PHENYLMETHYL)-1H-INDAZOLE

3-(PHENYLMETHYL)-1H-INDAZOLE - Names and Identifiers

Name	3-Benzyl-1H-indazole
Synonyms	3-benzyl-2H-indazole 3-Benzyl-1H-indazole 3-(PHENYLMETHYL)-1H-INDAZOLE 1H-indazole, 3-(phenylmethyl)- 1H-Indazole, 3-(phenylmethyl)-
CAS	4498-74-2
InChI	InChI=1/C14H12N2/c1-2-6-11(7-3-1)10-14-12-8-4-5-9-13(12)15-16-14/h1-9H,10H2,(H,15,16)

3-(PHENYLMETHYL)-1H-INDAZOLE - Physico-chemical Properties

Molecular Formula	C14H12N2
Molar Mass	208.26
Density	1.193±0.06 g/cm3(Predicted)
Melting Point	113-115 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4))
Boling Point	392.3±11.0 °C(Predicted)
Flash Point	110.3°C
Vapor Presure	0.00447mmHg at 25°C
pKa	14.45±0.40(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.679

3-(PHENYLMETHYL)-1H-INDAZOLE - Introduction

3-Benzyl-1H-indazole is an organic compound with the chemical formula C14H12N2. It is a white crystalline solid, soluble in some organic solvents such as ethanol, dimethyl sulfoxide and methylene chloride.

3-Benzyl-1H-indazole has a wide range of applications. It can be used as a pharmaceutical intermediate for the synthesis of various biologically active compounds. For example, it can be used to synthesize anti-inflammatory drugs, antibacterial drugs, anti-tumor drugs, etc. In addition, it can also be used to prepare dyes, pesticides and functional materials.

There are various methods for preparing 3-Benzyl-1H-indazole. One of the commonly used methods is the reaction of benzylamine with indolone to obtain the desired product by oxidation and reduction steps.

Regarding safety information, although 3-Benzyl-1H-indazole does not have clear toxicity data and hazardous characteristics, relevant safety measures should be paid attention to when handling and operating. Direct contact with skin and eyes should be avoided, and inhalation or ingestion should be avoided. Good ventilation and suitable personal protective equipment should be provided during operation. In addition, it should be stored in a dry, cool place, away from easily burning substances. When waste is disposed of, it should be disposed of in accordance with local environmental regulations. During use, the safe operation procedures of the chemical laboratory should be followed. If inhaled or taken by mistake, seek medical attention immediately.

Last Update：2024-04-09 20:52:54