Use | Application of 3-(3-alkyn-1-butyl)-3-(2-iodoethyl)-3h-bis-acridine for the synthesis of chemical probes, this three-function building block comprises a photoactivated diaziridine, an alkyne tag and an iodine synthesis handle. When attached to a ligand or pharmacophore via its iodinated Linker, this building block allows UV-induced covalent modification of biological targets via alkyne tags and has the potential for downstream applications. Used alone or in parallel with other multifunctional building blocks. |