3-(hydroxyimino)-2,3-dihydro-1H-indol-2-one
Isatin-3-oxime
CAS: 607-28-3
Molecular Formula: C8H6N2O2
3-(hydroxyimino)-2,3-dihydro-1H-indol-2-one - Names and Identifiers
| Name | Isatin-3-oxime |
| Synonyms | ISATIN-3-OXIME beta-Isatoxime BETA-ISATOXIME Isatin-3-oxime ISATIN-BETA-OXIME INDOLE-2,3-DIONE OXIME 3-oximeindole-2,3-dione indole-2,3-dione,3-oxime 2,3-INDOLINEDIONE 3-OXIME 3-hydroxyiminoindolin-2-one 3-(hydroxyamino)-2H-indol-2-one 3-(hydroxyimino)-2,3-dihydro-1H-indol-2-one |
| CAS | 607-28-3 |
| EINECS | 210-132-2 |
| InChI | InChI=1/C8H6N2O2/c11-8-7(10-12)5-3-1-2-4-6(5)9-8/h1-4,12H,(H,9,10,11) |
3-(hydroxyimino)-2,3-dihydro-1H-indol-2-one - Physico-chemical Properties
| Molecular Formula | C8H6N2O2 |
| Molar Mass | 162.15 |
| Density | 1.49±0.1 g/cm3(Predicted) |
| Melting Point | 228°C (dec.) |
| Boling Point | 400.5°C at 760 mmHg |
| Flash Point | 196°C |
| Vapor Presure | 4.43E-08mmHg at 25°C |
| Appearance | powder to crystal |
| Color | Light yellow to Amber to Dark green |
| BRN | 136198 |
| pKa | 9.19±0.20(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.706 |
| MDL | MFCD00014568 |
3-(hydroxyimino)-2,3-dihydro-1H-indol-2-one - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| RTECS | NL7980000 |
| Hazard Class | IRRITANT |
3-(hydroxyimino)-2,3-dihydro-1H-indol-2-one - Introduction
Isatin-3-oxime(Isatin-3-oxime) is an organic compound with the formula C8H6N2O2. It is a white or yellowish solid, soluble in alcohol and acid solvents, slightly soluble in water.
Isatin-3-oxime have multiple uses. First, it can be used as a dye intermediate. In the dye industry, Isatin-3-oxime can be reacted with phenolic compounds to produce indigo red dyes with brilliant colors. Secondly, Isatin-3-oxime can also be used in organic synthesis reactions as hydrogen oxidizing agents, reducing agents or building blocks for molecular scaffolds.
The method of preparing Isatin-3-oxime is relatively simple. One common method of preparation is to react isatin with a hydroxamic acid to form Isatin-3-oxime. This reaction process is generally carried out in an alcohol or acidic solvent, and the reaction time and reaction conditions can be adjusted according to specific conditions.
The Isatin-3-oxime is relatively stable under normal use conditions, but it is still necessary to pay attention to safety. It may cause irritation to the eyes and skin, so wear appropriate protective equipment during use. In addition, it should be stored in a cool, dry place to avoid contact with strong oxidants. It is important to follow safe operating procedures when handling and storing.
Isatin-3-oxime have multiple uses. First, it can be used as a dye intermediate. In the dye industry, Isatin-3-oxime can be reacted with phenolic compounds to produce indigo red dyes with brilliant colors. Secondly, Isatin-3-oxime can also be used in organic synthesis reactions as hydrogen oxidizing agents, reducing agents or building blocks for molecular scaffolds.
The method of preparing Isatin-3-oxime is relatively simple. One common method of preparation is to react isatin with a hydroxamic acid to form Isatin-3-oxime. This reaction process is generally carried out in an alcohol or acidic solvent, and the reaction time and reaction conditions can be adjusted according to specific conditions.
The Isatin-3-oxime is relatively stable under normal use conditions, but it is still necessary to pay attention to safety. It may cause irritation to the eyes and skin, so wear appropriate protective equipment during use. In addition, it should be stored in a cool, dry place to avoid contact with strong oxidants. It is important to follow safe operating procedures when handling and storing.
Last Update：2024-04-10 22:29:15
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