3-(p-Chlorophenethyl)picolinonitrile

3-(p-Chlorophenethyl)picolinonitrile - Names and Identifiers

Name	3-(p-Chlorophenethyl)picolinonitrile
Synonyms	3-(p-Chlorophenethyl)picolinonitrile 3(2-(3-Chloro phenyl)ethyl) cyano pyridine 3-(4-chloro-phenethyl)-pyridine-2-carbonitrile 3-[2-(4-Chlorophenyl)ethyl]-2-pyridinecarbonitrile 2-Pyridinecarbonitrile, 3-[2-(4-chlorophenyl)ethyl]-
CAS	31255-55-7

3-(p-Chlorophenethyl)picolinonitrile - Physico-chemical Properties

Molecular Formula	C14H11ClN2
Molar Mass	242.7
Density	1.23
Boling Point	375.7±32.0 °C(Predicted)
pKa	-0.14±0.10(Predicted)

3-(p-Chlorophenethyl)picolinonitrile - Introduction

3-(p-Chlorophenethyl)picolinonitrile is an organic compound with the chemical formula C14H11ClN2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid.
-Melting point: about 68-72°C.
-Solubility: Soluble in some organic solvents, such as methanol, chloroform and ethanol, insoluble in water.

Use:
- 3-(p-Chlorophenethyl)picolinonitrile can be used as a pharmaceutical intermediate in the treatment of depression and anxiety.
-It can also be used to synthesize other organic compounds, such as medicines, pesticides and dyes.

Preparation Method:
- 3-(p-Chlorophenethyl)picolinonitrile is generally synthesized by adding chlorophenylacetic acid and sulfuric acid to 2-picolinonitrile, and reacting with tetrabutylammonium hydroxide (TBAB) as a catalyst.

Safety Information:
- 3-(p-Chlorophenethyl)picolinonitrile should be careful to prevent contact with skin, eyes and respiratory tract during use and storage, and avoid inhalation or ingestion.
-It is irritating and may cause damage to the respiratory system, eyes and skin.
-In the operation, should wear protective gloves, protective glasses and masks, pay attention to good ventilation conditions.
-In case of accidental contact, rinse the area immediately with plenty of water and seek medical help.

Last Update：2024-04-09 15:18:01