Name | 3-AMINO-2-OXAZOLIDINONE |
Synonyms | AOZ NSC 38250 NSC 196570 NSC 111187 3-AMINO-OXAZOLIDINONE 3-AMINO-2-OXAZOLIDINONE 3-Amino-1,3-oxazolidin-2-one 3-azanyl-1,3-oxazolidin-2-one |
CAS | 80-65-9 |
EINECS | 201-299-2 |
Molecular Formula | C3H6N2O2 |
Molar Mass | 102.09 |
Density | 1.179 |
Melting Point | 65-67 °C |
Boling Point | 135 °C(Press: 0.7 Torr) |
Appearance | morphology neat |
pKa | 3.24±0.20(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,2-8°C |
Physical and Chemical Properties | Bioactive 3-Amino-2-oxazolidinone (AOZ) is a metabolite (metabolite) of furazolidinone (HY-B1336). 3-Amino-2-oxazolidinone as an indicator for the detection of furazolidinone residues. |
Use | Use an intermediate of the antibacterial agent furazolidone. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
WGK Germany | 3 |
HS Code | 29349990 |
Raw Materials | 2-Hydroxyethylhydrazine NSC 206120 Furazolidone |
BRN | 109430 |
It is obtained by nitrosation, cyclization and reduction of β-hydroxyethyl urea. Mix β-hydroxyethyl urea aqueous solution with sodium nitrite, cool to 0-3 ℃, add hydrochloric acid dropwise, keep the temperature below 28 ℃, finish the addition, raise the temperature to 40-45 ℃, and react for half an hour. Cool down to 0-3 ℃, then add sodium nitrite solution dropwise. Add crushed ice to cool down to -20 ℃, add iron powder to react for half an hour, filter, and the filtrate is 3-amino-2-oxazolidinone aqueous solution