3-AMine-5-fluoro-pyridine
3-amino-5-fluoropyridine
CAS: 210169-05-4
Molecular Formula: C5H5FN2
3-AMine-5-fluoro-pyridine - Names and Identifiers
| Name | 3-amino-5-fluoropyridine |
| Synonyms | 5-Fluoropyridin-3-amine 5-fluoropyridin-3-amine 3-Amine-5-fluoro-pyridin 3-PyridinaMine,5-fluoro- 3-amino-5-fluoropyridine 3-AMINO-5-FLUOROPYRIDINE 3-AMine-5-fluoro-pyridine 5-Fluoropyridin-3-ylamine 3-Pyridinamine,5-fluoro-(9CI) (Z)-4-(diethylamino)-1,1,1-trifluoro-but-3-en-2-one |
| CAS | 210169-05-4 |
| EINECS | 664-255-5 |
| InChI | InChI=1/C8H12F3NO/c1-3-12(4-2)6-5-7(13)8(9,10)11/h5-6H,3-4H2,1-2H3/b6-5- |
3-AMine-5-fluoro-pyridine - Physico-chemical Properties
| Molecular Formula | C5H5FN2 |
| Molar Mass | 112.11 |
| Density | 1.257±0.06 g/cm3(Predicted) |
| Melting Point | 86°C |
| Boling Point | 232.7±20.0 °C(Predicted) |
| Flash Point | 46.8°C |
| Vapor Presure | 3.29mmHg at 25°C |
| Appearance | Solid |
| Color | Light orange to Yellow to Green |
| pKa | 3.74±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.41 |
| MDL | MFCD00234073 |
3-AMine-5-fluoro-pyridine - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
3-AMine-5-fluoro-pyridine - Reference Information
| introduction | 3-amino -5-fluoropyridine is a white crystalline solid form. it is a prominent intermediate among many pyridine derivatives. because of its good biological activity, it is often used as an important raw material or intermediate for the synthesis of medicine and pesticides, and plays an important role in the synthesis of pyridine drugs. |
| use | 3-amino -5-fluoropyridine is an important industrial raw material, widely used in medicine, pesticides, dyes and other industries. Because pyridine ring has biological activity and has irreplaceable role of other groups or functional groups in the synthesis of drugs, it is a hot field in medical research. In the field of medicine, the derivatives of 3-amino-5-fluoropyridine are synthetic drugs for the treatment of duodenal ulcer, pantoprazole sodium, antidepressant SB-243213, vitamin B6 for the treatment of pregnancy vomiting, and bronchodilator bromdistigmine. It is an important intermediate for drugs such as pibuterol for the treatment of chronic obstructive pulmonary disease, piroxicam for the treatment of arthritis, and paliperidone. In the field of dyes, 3-amino-5-fluoropyridine is mainly used as a coupling agent for the synthesis of azo compounds. 4-nitro-2-amino-1-hydroxybenzene reacts with 2-amino-3-hydroxypyridine to form pyridinone dyes. |
Last Update：2024-04-09 02:00:07
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