3-Acetyl-6-chloro-4-phenyl-1H-quinolin-2-one
2(1H)-Quinolinone, 3-acetyl-6-chloro-4-phenyl-
CAS: 58375-08-9
Molecular Formula: C17H12ClNO2
3-Acetyl-6-chloro-4-phenyl-1H-quinolin-2-one - Names and Identifiers
3-Acetyl-6-chloro-4-phenyl-1H-quinolin-2-one - Physico-chemical Properties
| Molecular Formula | C17H12ClNO2 |
| Molar Mass | 297.74 |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD00116018 |
3-Acetyl-6-chloro-4-phenyl-1H-quinolin-2-one - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29334900 |
| Hazard Class | IRRITANT |
3-Acetyl-6-chloro-4-phenyl-1H-quinolin-2-one - Introduction
2(1H)-Quinolinone,-(2(1H)-Quinolinone,-) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: It is a yellow solid powder.
-Melting point: about 180-185°C.
-Solubility: Soluble in some organic solvents, such as chloroform, dimethyl sulfoxide and ether.
Use:
2(1H)-Quinolinone,-has a wide range of practical applications, including:
-Drugs: As drug intermediates, it can be used to synthesize some drugs, such as anti-inflammatory drugs and anti-cancer drugs.
-Pesticides: Can be used to synthesize certain pesticides and herbicides.
-Chemical research: It can be used as a catalyst or reducing agent in organic synthesis reactions.
Preparation Method:
2(1H)-Quinolinone,-can be prepared by the following steps:
-First, phenyl ketone is oxidized by an oxidation reaction to obtain hydroxyphenyl ketone.
-Hydroxyphenyl ketone is then chlorinated to give 6-chloro-2-hydroxy-4-phenylquinolin-3-one.
-Finally, an acetyl group is introduced at the 3-position through an acylation reaction to obtain the final product (1H)-Quinolinone, 2-.
Safety Information:
- 2(1H)-Quinolinone,-has limited toxicity data, but care should be taken to avoid contact with skin and eyes.
-When using or handling the compound, take appropriate personal protective measures, such as wearing protective gloves and safety glasses.
-If inhaled or ingested, seek medical attention immediately and provide relevant medication information to your doctor.
Nature:
-Appearance: It is a yellow solid powder.
-Melting point: about 180-185°C.
-Solubility: Soluble in some organic solvents, such as chloroform, dimethyl sulfoxide and ether.
Use:
2(1H)-Quinolinone,-has a wide range of practical applications, including:
-Drugs: As drug intermediates, it can be used to synthesize some drugs, such as anti-inflammatory drugs and anti-cancer drugs.
-Pesticides: Can be used to synthesize certain pesticides and herbicides.
-Chemical research: It can be used as a catalyst or reducing agent in organic synthesis reactions.
Preparation Method:
2(1H)-Quinolinone,-can be prepared by the following steps:
-First, phenyl ketone is oxidized by an oxidation reaction to obtain hydroxyphenyl ketone.
-Hydroxyphenyl ketone is then chlorinated to give 6-chloro-2-hydroxy-4-phenylquinolin-3-one.
-Finally, an acetyl group is introduced at the 3-position through an acylation reaction to obtain the final product (1H)-Quinolinone, 2-.
Safety Information:
- 2(1H)-Quinolinone,-has limited toxicity data, but care should be taken to avoid contact with skin and eyes.
-When using or handling the compound, take appropriate personal protective measures, such as wearing protective gloves and safety glasses.
-If inhaled or ingested, seek medical attention immediately and provide relevant medication information to your doctor.
Last Update：2024-04-09 21:01:54
