3-Amino-1-morpholin-4-yl-propan-1-onexHCl - Names and Identifiers
3-Amino-1-morpholin-4-yl-propan-1-onexHCl - Physico-chemical Properties
Molecular Formula | C7H15ClN2O2
|
Molar Mass | 194.66 |
Boling Point | 326.8°C at 760 mmHg |
Flash Point | 151.4°C |
Vapor Presure | 0.000211mmHg at 25°C |
Storage Condition | Sealed in dry,Room Temperature |
3-Amino-1-morpholin-4-yl-propan-1-onexHCl - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | R22 - Harmful if swallowed
R36 - Irritating to the eyes
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
Hazard Class | IRRITANT |
3-Amino-1-morpholin-4-yl-propan-1-onexHCl - Introduction
Also known as 3-amino-1-methyll-4-piperidone hydrochloride, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: A white crystalline solid.
-Melting point: about 175-180 ° C.
-Solubility: Soluble in water and alcohol, slightly soluble in non-polar solvents.
Use:
-As a pharmaceutical intermediate: HCL can be used to synthesize a variety of drugs, such as anti-cancer drugs, antidepressants, etc.
-As an organic synthesis reagent: It can be used as a condensing agent, Catalyst or intermediate in organic synthesis.
Method:
The preparation of HCL usually goes through the following steps:
1. The morpholine (piperidine) reacts with cyanoacetate to generate 3-morpholine propionate.
2.3-morpholine propionate is reacted with formamide to generate 3-morpholine propionamide.
3.3-morpholine propionamide reacts with ammonia or ammonia salt to generate 3-amino -1-morpholine -4-propane -1-one.
4. React amino -1-morpholine-4-propan-1-one with hydrochloric acid to generate the final oxyl HCL.
Safety Information:
The safety information of HCL is limited. As a chemical, it can cause irritation to the skin, eyes and respiratory system. Wear appropriate personal protective equipment such as lab gloves, goggles and protective masks when used or handled. At the same time, follow appropriate laboratory procedures and store them in a sealed, dry, well-ventilated place, away from ignition and combustibles.
Important note: Before using any chemical, please carefully read and follow the relevant safety data sheets and operating instructions to ensure safe operation and prevent potential risks.
Last Update:2024-04-09 21:11:58