3-Amino-2,2-dimethylpropionamide
3-Amino-2,2-dimethylpropionamide
CAS: 324763-51-1
Molecular Formula: C5H12N2O
3-Amino-2,2-dimethylpropionamide - Names and Identifiers
| Name | 3-Amino-2,2-dimethylpropionamide |
| Synonyms | Aliskiren Inter-5 3-aMino-2,2-diMethyl- Aliskiren intermediates 3-AMino-2,2-diMethylpropinaMid 3-Amino-2,2-dimethylpropanamide 3-Amino-2,2-dimethylpropionamide Propanamide, 3-amino-2,2-dimethyl- 2-(aminomethyl)-2-methylpropanamide 3-amino-2,2-dimethylpropionic acid amide |
| CAS | 324763-51-1 |
| EINECS | 1806241-263-5 |
| InChI | InChI=1/C5H12N2O/c1-5(2,3-6)4(7)8/h3,6H2,1-2H3,(H2,7,8) |
3-Amino-2,2-dimethylpropionamide - Physico-chemical Properties
| Molecular Formula | C5H12N2O |
| Molar Mass | 116.16 |
| Density | 1.004 |
| Melting Point | 74-75 °C |
| Boling Point | 271 °C |
| Flash Point | 117 °C |
| Solubility | DMSO, Methanol |
| Vapor Presure | 0.00675mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 16.45±0.50(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.47 |
3-Amino-2,2-dimethylpropionamide - Introduction
3-Amino-2,2-dimethylpropionamide is an organic compound with the chemical formula C6H14N2O. It is a colorless or pale yellow crystalline solid with a peculiar ammonia odor. It is soluble in water and many organic solvents.
3-Amino-2,2-dimethylpropionamide is mainly used for amine-based protective agents and intermediates in organic synthesis. It can be used as a raw material for the synthesis of peptides or hormonal drugs. In addition, it can also be used in the synthesis of pigments and dyes, as well as in the field of pesticides and medicine.
There are many methods for preparing 3-Amino-2,2-dimethylpropionamide, usually through amidation reaction. A specific step is the reaction of 3-amino -2, 2-dimethylpropionic acid with a suitable acylating agent, such as acid chloride or anhydride, to produce 3-Amino-2,2-dimethylpropionamide.
Although 3-Amino-2,2-dimethylpropionamide is often used as a chemical reagent in the laboratory, some safety precautions need to be paid attention to during use. It is a kind of combustible material, and it is easy to burn when encountering open flame. At the same time, contact with skin and eyes may cause irritation and damage, so it is necessary to wear appropriate protective equipment and maintain good ventilation during operation. When stored, it should be stored in a cool, dry place, away from flammables and oxidants.
3-Amino-2,2-dimethylpropionamide is mainly used for amine-based protective agents and intermediates in organic synthesis. It can be used as a raw material for the synthesis of peptides or hormonal drugs. In addition, it can also be used in the synthesis of pigments and dyes, as well as in the field of pesticides and medicine.
There are many methods for preparing 3-Amino-2,2-dimethylpropionamide, usually through amidation reaction. A specific step is the reaction of 3-amino -2, 2-dimethylpropionic acid with a suitable acylating agent, such as acid chloride or anhydride, to produce 3-Amino-2,2-dimethylpropionamide.
Although 3-Amino-2,2-dimethylpropionamide is often used as a chemical reagent in the laboratory, some safety precautions need to be paid attention to during use. It is a kind of combustible material, and it is easy to burn when encountering open flame. At the same time, contact with skin and eyes may cause irritation and damage, so it is necessary to wear appropriate protective equipment and maintain good ventilation during operation. When stored, it should be stored in a cool, dry place, away from flammables and oxidants.
Last Update：2024-04-09 21:11:58
