3-Amino-2-bromobenzotrifluoride

3-Amino-2-bromobenzotrifluoride - Names and Identifiers

Name	2-bromo-3-(trifluoromethyl)aniline
Synonyms	Einecs 261-261-6 3-Amino-2-bromobenzotrifluoride 2-bromo-3-(trifluoromethyl)aniline 2-BroMo-3-trifluoroMethyl-phenylaMine 2-broMo-3-(trifluoroMethyl)benzenaMine benzenamine, 2-bromo-3-(trifluoromethyl)- Benzenamine, 2-bromo-3-(trifluoromethyl)- 3-AMino-2-broMobenzotrifluoride[2-BroMo-3-(trifluoroMethyl)aniline] 2-Bromo-3-(trifluoromethyl)aniline, 2-Bromo-alpha,alpha,alpha-trifluoro-m-toluidine
CAS	58458-10-9
EINECS	261-261-6
InChI	InChI=1/C7H5BrF3N/c8-6-4(7(9,10)11)2-1-3-5(6)12/h1-3H,12H2

3-Amino-2-bromobenzotrifluoride - Physico-chemical Properties

Molecular Formula	C7H5BrF3N
Molar Mass	240.02
Density	1.697±0.06 g/cm3(Predicted)
Boling Point	228.9±40.0 °C(Predicted)
Flash Point	92.2°C
Vapor Presure	0.0716mmHg at 25°C
Appearance	Solid
Color	Off-white
pKa	1.31±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.522

3-Amino-2-bromobenzotrifluoride - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	6.1

3-Amino-2-bromobenzotrifluoride - Introduction

2-bromo-3-(trifluoromethyl)aniline, the chemical name is 2-bromo-3-(trifluoromethyl)aniline, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: A white crystalline powder.
-Solubility: It can be dissolved in organic solvents such as ethanol and dimethylformamide, but is insoluble in water.
-Melting point: about 60-61°C.
-Molecular formula: C7H5BrF3N.

Use:
- 2-bromo-3-(trifluoromethyl)aniline are commonly used in various reactions in organic synthesis, such as substitution reactions and catalytic reactions.
-It is also used as a raw material for pesticides and pharmaceutical intermediates.

Preparation Method:
2-bromo-3-(trifluoromethyl)aniline can be synthesized by the following steps:
1. First, bromobenzene is reacted with sodium tetrafluoroacetate in an organic solvent to obtain 2-bromobenzotrifluoride.
2. reacting 2-bromo-benzotrifluoride with aniline, and introducing an amino group at position 3 through an electrophilic substitution reaction to obtain the final product 2-bromo-3-(trifluoromethyl)aniline.

Safety Information:
- 2-bromo-3-(trifluoromethyl)aniline may be harmful to human health, so wear appropriate protective equipment such as gloves and glasses during use.
-It should be stored in a dry and ventilated place to avoid contact with oxidants and strong acids.
-Observe local safety practices during handling or disposal.

Last Update：2024-04-09 21:01:54