3-Amino-6-fluoropyridine
5-Amino-2-fluoropyridine
CAS: 1827-27-6
Molecular Formula: C5H5FN2
3-Amino-6-fluoropyridine - Names and Identifiers
| Name | 5-Amino-2-fluoropyridine |
| Synonyms | 6-FLUORO-3-PYRIDINAMINE 2-FLUOROPYRIDIN-5-AMINE 6-FLUOROPYRIDIN-3-AMINE 2-Fluoro-5-aminopyridine 5-Amino-2-fluoropyridine 3-Amino-6-fluoropyridine 5-AMINO-2-FLUOROPYRIDINE 2-FLUORO-5-AMINO PYRIDINE 6-FLUORO-PYRIDIN-3-YLAMINE |
| CAS | 1827-27-6 |
| EINECS | 675-011-2 |
| InChI | InChI=1/C7H4F2O3/c8-4-2-1-3(7(11)12)6(10)5(4)9/h1-2,10H,(H,11,12) |
3-Amino-6-fluoropyridine - Physico-chemical Properties
| Molecular Formula | C5H5FN2 |
| Molar Mass | 112.11 |
| Density | 1.257±0.06 g/cm3(Predicted) |
| Melting Point | 86-87°C |
| Boling Point | 264.0±20.0 °C(Predicted) |
| Flash Point | 124.1°C |
| Vapor Presure | 0.00168mmHg at 25°C |
| Appearance | Solid |
| pKa | 2?+-.0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.557 |
| MDL | MFCD01632180 |
3-Amino-6-fluoropyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
3-Amino-6-fluoropyridine - Introduction
5-Amino-2-fluoropyridine is an organic compound with the chemical formula C5H5FN2. The following is a description of its nature, use, formulation and safety information:
Nature:
- 5-Amino-2-fluoropyridine is a white to pale yellow crystal with a special sense of smell.
-It is solid under normal temperature and pressure and has high thermal stability.
- 5-Amino-2-fluoropyridine is almost insoluble in water, but can be dissolved in some organic solvents.
Use:
- 5-Amino-2-fluoropyridine is commonly used as a reagent in organic synthesis to catalyze and promote the progress of chemical reactions.
-It also has some applications in the pharmaceutical field and can be used as intermediates for the synthesis of certain drugs.
-In addition, 5-Amino-2-fluoropyridine can also be used in the electronics and polymer industries.
Method:
- 5-Amino-2-fluoropyridine can be obtained by the reaction of 2-fluoropyridine and ammonia. The reaction is typically carried out in an inert atmosphere, for example under nitrogen.
-During the reaction process, it is necessary to control the reaction temperature and reaction time, and carry out appropriate process optimization to improve the yield and purity.
Safety Information:
- 5-Amino-2-fluoropyridine is an irritating compound, and adequate ventilation and personal protective equipment are necessary during handling and use.
-It may be dangerous at high temperatures or in contact with strong oxidants, so it is necessary to pay attention to fire and explosion prevention measures during storage and handling.
-When handling 5-Amino-2-fluoropyridine, avoid direct contact with skin and eyes, and use protective gloves and goggles if necessary.
-When the compound is accidentally inhaled or ingested, seek medical attention.
Nature:
- 5-Amino-2-fluoropyridine is a white to pale yellow crystal with a special sense of smell.
-It is solid under normal temperature and pressure and has high thermal stability.
- 5-Amino-2-fluoropyridine is almost insoluble in water, but can be dissolved in some organic solvents.
Use:
- 5-Amino-2-fluoropyridine is commonly used as a reagent in organic synthesis to catalyze and promote the progress of chemical reactions.
-It also has some applications in the pharmaceutical field and can be used as intermediates for the synthesis of certain drugs.
-In addition, 5-Amino-2-fluoropyridine can also be used in the electronics and polymer industries.
Method:
- 5-Amino-2-fluoropyridine can be obtained by the reaction of 2-fluoropyridine and ammonia. The reaction is typically carried out in an inert atmosphere, for example under nitrogen.
-During the reaction process, it is necessary to control the reaction temperature and reaction time, and carry out appropriate process optimization to improve the yield and purity.
Safety Information:
- 5-Amino-2-fluoropyridine is an irritating compound, and adequate ventilation and personal protective equipment are necessary during handling and use.
-It may be dangerous at high temperatures or in contact with strong oxidants, so it is necessary to pay attention to fire and explosion prevention measures during storage and handling.
-When handling 5-Amino-2-fluoropyridine, avoid direct contact with skin and eyes, and use protective gloves and goggles if necessary.
-When the compound is accidentally inhaled or ingested, seek medical attention.
Last Update：2024-04-09 20:52:54
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