3-Amino-α-methyl-benzenemethanamine
3-(1-AMINO-ETHYL)-PHENYLAMINE
CAS: 129725-48-0
Molecular Formula: C8H12N2
3-Amino-α-methyl-benzenemethanamine - Names and Identifiers
3-Amino-α-methyl-benzenemethanamine - Physico-chemical Properties
| Molecular Formula | C8H12N2 |
| Molar Mass | 136.19 |
| Density | 1.056g/cm3 |
| Melting Point | 51-56°C |
| Boling Point | 266.5°C at 760 mmHg |
| Flash Point | >110℃ |
| Vapor Presure | 0.00863mmHg at 25°C |
| Storage Condition | Room Temprature |
| Refractive Index | 1.59 |
3-Amino-α-methyl-benzenemethanamine - Risk and Safety
| Risk Codes | 43 - May cause sensitization by skin contact |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
3-Amino-α-methyl-benzenemethanamine - Introduction
1-(3-Aminophenyl) ethylamine, also known as p-aminophenethylamine, has the chemical formula C8H11N. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Common is a colorless crystalline solid;
-Melting point: about 38-40°C;
-Boiling point: approximately 225°C;
-Solubility: Soluble in polar solvents such as water, ethanol and chloroform.
Use:
1-(3-Aminophenyl) ethylamine has many applications, including:
-Chemical synthesis: It can be used as an organic synthesis intermediate for the preparation of heterocyclic compounds, dyes and fluorescent dyes, etc;
-Drug: It is used as a precursor or intermediate of drugs for the synthesis of anti-cancer drugs, neurotransmitter drugs, etc;
-Adhesive: Due to the reactivity of its amine group and benzene ring, it can be used as a raw material for adhesives and adhesives.
Preparation Method:
1-(3-Aminophenyl) ethylamine has two main synthetic methods:
-reaction of aminoethylbenzene and benzylidene bromide: reacting aminoethylbenzene with benzylidene bromide under alkali catalysis to generate 1-(3-aminophenyl) ethylamine;
-Grignard reaction of acetophenone: acetophenone is reacted with ethyl phosphite in the presence of hydroxide to generate 1-(3-aminophenyl) ethylamine.
Safety Information:
- 1-(3-Aminophenyl) ethylamine is a chemical and should be stored in a dry, well-ventilated place, away from open flames and heat sources.
-Wear appropriate personal protective equipment such as gloves, safety goggles and protective masks to avoid contact with skin and inhalation when in use.
-During handling and storage, care should be taken to avoid mixing with oxidants and acids to avoid dangerous reactions.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical attention.
Please note that the safe handling and use of chemicals is very important. It is recommended to use 1-(3-aminophenyl) ethylamine in accordance with relevant regulations and safety guidelines.
Nature:
-Appearance: Common is a colorless crystalline solid;
-Melting point: about 38-40°C;
-Boiling point: approximately 225°C;
-Solubility: Soluble in polar solvents such as water, ethanol and chloroform.
Use:
1-(3-Aminophenyl) ethylamine has many applications, including:
-Chemical synthesis: It can be used as an organic synthesis intermediate for the preparation of heterocyclic compounds, dyes and fluorescent dyes, etc;
-Drug: It is used as a precursor or intermediate of drugs for the synthesis of anti-cancer drugs, neurotransmitter drugs, etc;
-Adhesive: Due to the reactivity of its amine group and benzene ring, it can be used as a raw material for adhesives and adhesives.
Preparation Method:
1-(3-Aminophenyl) ethylamine has two main synthetic methods:
-reaction of aminoethylbenzene and benzylidene bromide: reacting aminoethylbenzene with benzylidene bromide under alkali catalysis to generate 1-(3-aminophenyl) ethylamine;
-Grignard reaction of acetophenone: acetophenone is reacted with ethyl phosphite in the presence of hydroxide to generate 1-(3-aminophenyl) ethylamine.
Safety Information:
- 1-(3-Aminophenyl) ethylamine is a chemical and should be stored in a dry, well-ventilated place, away from open flames and heat sources.
-Wear appropriate personal protective equipment such as gloves, safety goggles and protective masks to avoid contact with skin and inhalation when in use.
-During handling and storage, care should be taken to avoid mixing with oxidants and acids to avoid dangerous reactions.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical attention.
Please note that the safe handling and use of chemicals is very important. It is recommended to use 1-(3-aminophenyl) ethylamine in accordance with relevant regulations and safety guidelines.
Last Update：2024-04-09 21:04:16
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