3-BROMO-N-TERT-BUTYLBENZENESULPHONAMIDE

3-BROMO-N-TERT-BUTYLBENZENESULPHONAMIDE - Names and Identifiers

Name	3-bromo-N-tert-butylbenzenesulfonamide
Synonyms	3-bromo-N-tert-butylbenzenesulfonamide 3-Bromo-N-tert-butylbenzenesulfonamide N-TERT-BUTYL 3-BROMOBENZENESULFONAMIDE 3-BROMO-N-TERT-BUTYLBENZENESULPHONAMIDE 3-Bromo-N-(tert-butyl)benzenesulphonamide Benzenesulfonamide, 3-bromo-N-(1,1-dimethylethyl)- BenzenesulfonaMide, 3-broMo-N-(1,1-diMethylethyl)-
CAS	308283-47-8
InChI	InChI=1/C10H14BrNO2S/c1-10(2,3)12-15(13,14)9-6-4-5-8(11)7-9/h4-7,12H,1-3H3

3-BROMO-N-TERT-BUTYLBENZENESULPHONAMIDE - Physico-chemical Properties

Molecular Formula	C10H14BrNO2S
Molar Mass	292.19
Density	1.419±0.06 g/cm3(Predicted)
Melting Point	68-70
Boling Point	365.3±44.0 °C(Predicted)
Flash Point	174.7°C
Vapor Presure	1.58E-05mmHg at 25°C
pKa	11.44±0.50(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.549

3-BROMO-N-TERT-BUTYLBENZENESULPHONAMIDE - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

3-BROMO-N-TERT-BUTYLBENZENESULPHONAMIDE - Introduction

It is an organic compound with the chemical formula C10H14BrNO2S. The following is the relevant information:

Nature:
-Appearance: White crystal or crystalline powder
-Melting point: About 123-125 degrees Celsius
-Boiling point: About 312 degrees Celsius
-Solubility: Easily soluble in organic solvents such as ether and chloroform, almost insoluble in water

Use:
-is an important organic synthesis intermediate, widely used in the field of medicine and pesticide.
-It can be used to synthesize physiologically active compounds, such as anticancer agents, antiviral agents and antibacterial agents.

Method:
It can be synthesized by the following steps:
1. Take 3-bromobenzene sulfonamide and react it with tert-butyl Grimm's reagent to generate the corresponding Grenard's reagent.
2. The reactant and nucleophilic reagent Cuprous bromide (cuprus bromide) reaction, halogenation reaction.
3. Finally, purify the obtained product through crystallization and filtration steps to obtain Ni.

Safety Information:
-is a chemical, the skin, eyes and respiratory tract have a stimulating effect, use should pay attention to protective measures.
-Avoid inhalation, swallowing or contact with the compound.
-Wear protective gloves, goggles and protective mask during use.
-Avoid contact with oxidants during storage, avoid high temperatures and fire sources.
-If contact or ingestion occurs, seek medical advice immediately.

Last Update：2024-04-09 21:00:56