3-Bromo-2-(4-ethylpiperazino)-5-methylpyridine
1-(3-Bromo-5-methylpyridin-2-yl)-4-ethylpiperazine
CAS: 1187386-39-5
Molecular Formula: C12H18BrN3
3-Bromo-2-(4-ethylpiperazino)-5-methylpyridine - Names and Identifiers
3-Bromo-2-(4-ethylpiperazino)-5-methylpyridine - Physico-chemical Properties
| Molecular Formula | C12H18BrN3 |
| Molar Mass | 284.2 |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD12913990 |
3-Bromo-2-(4-ethylpiperazino)-5-methylpyridine - Introduction
1-(5-methylpyridin-2-yl)-4-ethylpiperazine(1-(3-bromo-5-methylpyridin-2-yl)-4-ethylpiperazine) is an organic compound. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: The compound is a white solid.
-Molecular formula: C13H19BrN3
-Molecular weight: 292.218g/mol
-Melting point: about 99-100°C
-Boiling point: about 459.9°C
-Solubility: Soluble in some organic solvents, such as chloroform and ethanol.
Use:
-Chemical research: 1-(1)-4-ethylpiperazine can be used as an intermediate in organic synthesis and used to synthesize other organic compounds.
-Pharmaceutical Research: This compound is structurally related to piperazines and may have potential applications in the medical field, such as drug research and development as a possible pharmaceutical active moiety.
Preparation Method:
1-(-)-4-piperazine can be synthesized by the following synthetic route:
1. First, 2,5-dibromo-3-methylpyridine is reacted with ethylamine through a chemical reaction to prepare 3-(2-aminoethyl)-2,5-dibromopyridine.
2. Then, 3-(2-aminoethyl)-2,5-dibromopyridine is reacted with ethyl magnesium bromide under appropriate experimental conditions to prepare 1-(3-bromo-5-methylpyridin-2-yl)-4-ethylpiperazine.
3. Finally, bromination reaction is carried out in the process of generating 1-(3-bromo-5-methylpyridin-2-yl)-4-ethylpiperazine by adding hydrogen bromide to prepare the final product 1-(pyridine)-4-ethylpiperazine.
Safety Information:
1-4-ethylazine has limited safety information and needs to be handled with caution.
-This is an organic compound and requires compliance with laboratory safety procedures and precautions such as gloves, goggles and laboratory coats.
-Avoid direct contact with skin, eyes and respiratory tract.
-If accidentally inhaled or exposed to the compound, the affected area should be cleaned immediately and medical advice should be sought in time.
-Store and dispose of the compound properly, following local chemical waste disposal regulations.
Nature:
-Appearance: The compound is a white solid.
-Molecular formula: C13H19BrN3
-Molecular weight: 292.218g/mol
-Melting point: about 99-100°C
-Boiling point: about 459.9°C
-Solubility: Soluble in some organic solvents, such as chloroform and ethanol.
Use:
-Chemical research: 1-(1)-4-ethylpiperazine can be used as an intermediate in organic synthesis and used to synthesize other organic compounds.
-Pharmaceutical Research: This compound is structurally related to piperazines and may have potential applications in the medical field, such as drug research and development as a possible pharmaceutical active moiety.
Preparation Method:
1-(-)-4-piperazine can be synthesized by the following synthetic route:
1. First, 2,5-dibromo-3-methylpyridine is reacted with ethylamine through a chemical reaction to prepare 3-(2-aminoethyl)-2,5-dibromopyridine.
2. Then, 3-(2-aminoethyl)-2,5-dibromopyridine is reacted with ethyl magnesium bromide under appropriate experimental conditions to prepare 1-(3-bromo-5-methylpyridin-2-yl)-4-ethylpiperazine.
3. Finally, bromination reaction is carried out in the process of generating 1-(3-bromo-5-methylpyridin-2-yl)-4-ethylpiperazine by adding hydrogen bromide to prepare the final product 1-(pyridine)-4-ethylpiperazine.
Safety Information:
1-4-ethylazine has limited safety information and needs to be handled with caution.
-This is an organic compound and requires compliance with laboratory safety procedures and precautions such as gloves, goggles and laboratory coats.
-Avoid direct contact with skin, eyes and respiratory tract.
-If accidentally inhaled or exposed to the compound, the affected area should be cleaned immediately and medical advice should be sought in time.
-Store and dispose of the compound properly, following local chemical waste disposal regulations.
Last Update：2024-04-09 21:01:54
