3-Bromo-2-methoxy-5-trifluoromethylpyridine

3-Bromo-2-methoxy-5-trifluoromethylpyridine - Names and Identifiers

Name	Bromides
Synonyms	Bromides (3-Bromobenzoyl)pyrrolidine 6-Bromo-N-methylpicolinamide 6-Bromo-2-isopropoxypyridine 2-Bromo-6-isopropoxypyridine 1-Bromo-4-pentylcyclohex-1-ene 1-Bromo-4,4-dimethylcyclohex-1-ene 1-(5-Bromo-2-nitrophenyl)pyrrolidine 1-Bromo-4-fluoro-2-isopropoxybenzene 8-bromo-6-(trifluoromethoxy)quinoline (3-Bromophenyl)(pyrrolidin-1-yl)methanone 3-Bromo-2-methoxy-5-trifluoromethylpyridine ((4-Bromo-3-methylphenyl)carbonyl)morpholine 3-bromo-2-methoxy-5-(trifluoromethyl)pyridine (4-Bromo-3-methylphenyl)(morpholino)methanone S-(4-Methoxybenzyl) 4-bromo-2-fluorothiophenol (4-Bromo-2-fluorophenyl)(4-methoxybenzyl)sulfane (4-Bromo-3-methylphenyl)(pyrrolidin-1-yl)methanone 2-(1-(4-Bromophenyl)-1H-1,2,3-triazol-4-yl)propan-2-ol
CAS	124432-63-9
InChI	InChI=1/C7H5BrF3NO/c1-13-6-5(8)2-4(3-12-6)7(9,10)11/h2-3H,1H3

3-Bromo-2-methoxy-5-trifluoromethylpyridine - Physico-chemical Properties

Molecular Formula	C7H5BrF3NO
Molar Mass	256.02
Density	1.637±0.06 g/cm3(Predicted)
Melting Point	45-46°C
Boling Point	86-88 °C(Press: 21 Torr)
Flash Point	72.7°C
Solubility	Dichloromethane; Ethyl Acetate; Methanol
Vapor Presure	0.557mmHg at 25°C
Appearance	White powder
Color	White
pKa	-1.38±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.47
MDL	MFCD09972202
Physical and Chemical Properties	Storage Conditions: Keep Cold

3-Bromo-2-methoxy-5-trifluoromethylpyridine - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT

3-Bromo-2-methoxy-5-trifluoromethylpyridine - Introduction

3-Bromo-2-methoxy-5-trifluoromethylpyridine is an organic compound, also known as BTMFP. The following is detailed information about its nature, use, formulation and safety information:

Nature:
-Appearance: Common colorless or light yellow liquid or solid, with a special smell.
-Melting point: about 30-32 degrees Celsius.
-Boiling point: about 150-152 degrees Celsius.
-Density: about 1.8 g/ml.
-Low solubility in water, soluble in common organic solvents such as alcohols, ethers and ketones.

Use:
-3-Bromo-2-methoxy-5-trifluoromethylpyridine is mainly used in the field of organic synthesis.
-As a reagent, it can participate in a series of chemical reactions, such as fluorination reaction, thermal expansion and contraction (Thermal Expansion Cold Shrink) reaction and other olefin chemical reactions.
-In chemical research, it can also be used as an intermediate to participate in the synthesis of other organic compounds.

Preparation Method:
-3-Bromo-2-methoxy-5-trifluoromethylpyridine can be prepared by a variety of methods, one of which is the reaction of 3-bromo-5-trifluoromethylpyridine and methanol.
-The reaction process needs to be carried out under appropriate temperature and reaction conditions. Generally, it is necessary to control the reaction time and the ratio of reactants.

Safety Information:
-3-Bromo-2-methoxy-5-trifluoromethylpyridine is irritating to the eyes and skin, and direct contact should be avoided.
-Wear protective gloves and glasses when using, and make sure to operate in a well-ventilated environment.
-If accidentally swallowed or inhaled, seek medical attention immediately and provide information.

Last Update：2024-04-09 02:00:41