3-Bromo-2-trifluoromethylpyridine

3-Bromo-2-trifluoromethylpyridine - Names and Identifiers

Name	3-Bromo-2-trifluoromethylpyridine
Synonyms	Halides 4-chloro-2-piperidin-1-ylpyridine 3-Bromo-2-trifluoromethylpyridine 3-Bromo-2-(trifluoromethyl)pyridine 4-Bromo-1H-pyrazole, N1-BOC protected 5-[(2,3-dichlorophenoxy)methyl]-1,3,4-oxadiazol-2(3h)-one 5-(4-bromo-3-methoxythien-2-yl)-1,3,4-oxadiazol-2(3h)-one 5-[(e)-2-(2-chloro-3,4-dimethoxyphenyl)vinyl]-1,3,4-oxadiazol-2(3h)-one
CAS	590371-58-7
InChI	InChI=1/C6H3BrF3N/c7-4-2-1-3-11-5(4)6(8,9)10/h1-3H

3-Bromo-2-trifluoromethylpyridine - Physico-chemical Properties

Molecular Formula	C6H3BrF3N
Molar Mass	225.99
Density	1.707±0.06 g/cm3(Predicted)
Melting Point	34-36 °C(Solv: hexane (110-54-3))
Boling Point	97-99 °C(Press: 35 Torr)
Flash Point	53.73°C
Vapor Presure	2.486mmHg at 25°C
pKa	-1.80±0.22(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.471

3-Bromo-2-trifluoromethylpyridine - Risk and Safety

UN IDs	UN2811
Hazard Class	IRRITANT

3-Bromo-2-trifluoromethylpyridine - Introduction

It is an organic compound with the chemical formula C6H3BrF3N. It is a colorless to pale yellow liquid with a special odor.

It has a wide range of applications in organic synthesis. It can be used as an important intermediate for drug synthesis, especially for the synthesis of anticancer drugs. In addition, it can also be used in the preparation of pesticides and the production of chemical reagents.

The method of preparation is relatively simple. One commonly used method is by reacting pyridine with 3-bromo-2-trifluoromethylphenol.

Regarding safety information, is a corrosive compound that needs to be handled with care. It can cause irritation and damage to the eyes, skin and respiratory tract. Wear appropriate protective equipment such as gloves, goggles and protective clothing during use. Operate under closed ventilation conditions to avoid inhalation of its vapors. If it comes into contact with skin or eyes, rinse immediately with plenty of water and seek medical attention. During storage and transportation, care should be taken to prevent contact with strong oxidants and combustibles to avoid fire and explosion.

Last Update：2024-04-09 20:52:54