3-Bromo-5-Chloro-2-Cyanopyridine

3-Bromo-5-Chloro-2-Cyanopyridine - Names and Identifiers

Name	3-bromo-5-chloropyridine-2-carbonitrile
Synonyms	3-BROMO-5-CHLOROPICOLINOITRILE 3-BroMo-5-chloropicolinonitrile 3-Bromo-5-chloro-2-cyanopyridine 3-broMo-2-cyano-5-chloropyridine 3-Bromo-5-Chloro-2-Cyanopyridine 3-bromo-5-chloro-2-Pyridinecarbonitrile 3-bromo-5-chloropyridine-2-carbonitrile 2-Pyridinecarbonitrile, 3-bromo-5-chloro-
CAS	760207-83-8
InChI	InChI=1/C6H2BrClN2/c7-5-1-4(8)3-10-6(5)2-9/h1,3H

3-Bromo-5-Chloro-2-Cyanopyridine - Physico-chemical Properties

Molecular Formula	C6H2BrClN2
Molar Mass	217.45
Density	1.85±0.1 g/cm3(Predicted)
Boling Point	297.5±40.0 °C(Predicted)
Flash Point	133.718°C
Vapor Presure	0.001mmHg at 25°C
pKa	-4.96±0.20(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.629

3-Bromo-5-Chloro-2-Cyanopyridine - Introduction

It is an organic compound with the chemical formula C6H2BrClN2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: It is a solid with white to light yellow crystals.
-Solubility: It is soluble in some polar solvents (such as alcohols, ethers and dimethylformamide).
-Melting point and boiling point: Its melting point is about 85-87°C.
-Chemical properties: It can be used as a ligand to participate in reactions such as chloride and bromide, and can be used in organic synthesis reactions.

Use:
-It can be used as an intermediate in organic synthesis for the synthesis of other drugs, pesticides and chemicals.
-It can also be used to synthesize natural products and other organic compounds containing pyridine structure.

Preparation Method:
It can be synthesized by the following steps:
1. In dichloromethane or chloroform, 2-cyano -3-bromine pyridine and silver chloride reaction, the formation of silver salt.
2. The above silver salt is reacted with trifluoroacetic acid in dichloromethane to generate phosphonium.

Safety Information:
-should be stored in a cool, dry place, away from direct sunlight and moisture.
-During operation, wear appropriate protective equipment, such as gloves, glasses and laboratory coats, to avoid contact with skin and eyes.
-Observe relevant safe operation guidelines during storage and handling, and follow local regulations and codes.

Last Update：2024-04-09 02:00:48