3-Bromocatechol
3-BROMOBENZENE-1,2-DIOL
CAS: 14381-51-2
Molecular Formula: C6H5BrO2
3-Bromocatechol - Names and Identifiers
| Name | 3-BROMOBENZENE-1,2-DIOL |
| Synonyms | 3-Bromocatechol 3-Bromopyrocatechol 3-bromo-1,2-benzenediol 3-BROMOBENZENE-1,2-DIOL 3-Bromo-1,2-benzenediol 1,2-Benzenediol, 3-bromo- Phloroglucinol Impurity 30 2,3-dihydroxy-broMobenzene 1-Bromo-2,3-dihydroxybenzene |
| CAS | 14381-51-2 |
| InChI | InChI=1/C6H5BrO2/c7-4-2-1-3-5(8)6(4)9/h1-3,8-9H |
| InChIKey | JPBDMIWPTFDFEU-UHFFFAOYSA-N |
3-Bromocatechol - Physico-chemical Properties
| Molecular Formula | C6H5BrO2 |
| Molar Mass | 189.01 |
| Density | 1.844 |
| Melting Point | 40-41℃ |
| Boling Point | 243℃ |
| Flash Point | 101℃ |
| Solubility | Soluble in organic solvents. |
| Vapor Presure | 0.0216mmHg at 25°C |
| Appearance | Solid |
| Color | White to Gray to Brown |
| pKa | 8.26±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.657 |
| MDL | MFCD00869768 |
3-Bromocatechol - Introduction
3-BROMOBENZENE-1,2-DIOL is an organic compound with the chemical formula C6H4(OH)Br, also known as Bromophenol Blue or Bromophenol Blue. The following describes its nature, use, preparation and safety information:
Nature:
3-BROMOBENZENE-1,2-DIOL is a dark blue crystalline powder, soluble in alcohol and phenolic solvents, slightly soluble in water. It is yellow in acidic solution and blue in alkaline solution.
Use:
3-BROMOBENZENE-1,2-DIOL is widely used in chemical analysis, biochemistry and biological experiments. The Main uses include the following:
1. Acid-base indicator: it can show different colors in acid-base solution, commonly used in acid-base titration, acid-base neutralization point determination.
2. DNA gel electrophoresis: It can be used as a nucleic acid dye in DNA gel electrophoresis to detect the size of DNA fragments.
3. Protein electrophoresis: It can also be used as a dye in protein electrophoresis for detection of protein separation and quantification.
4. Biological development: It can be used as a developer in biological imaging to detect the presence and quantification of biological molecules.
Method:
There are two main methods for preparing 3-BROMOBENZENE-1,2-DIOL:
1. Bromination reaction of nitrobenzene, and then reduction reaction to obtain 3-bromo O-aniline, and finally through oxidation reaction to obtain 3-BROMOBENZENE-1,2-DIOL.
2.3-BROMOBENZENE-1,2-DIOL was obtained by bromination of Catechol.
Safety Information:
3-BROMOBENZENE-1,2-DIOL is an organic compound with certain toxicity. Contact with skin, eyes and respiratory tract may cause irritation and burns, so wear appropriate protective equipment such as gloves and glasses when used. During use or storage, contact with strong oxidants, strong acids and other substances should be avoided to avoid dangerous reactions. In addition, care should be taken to avoid inhalation of its dust or solution, regular ventilation, to ensure good ventilation of the operating area. Such as accidental contact or misuse, should immediately clean the affected parts, and timely medical treatment.
Nature:
3-BROMOBENZENE-1,2-DIOL is a dark blue crystalline powder, soluble in alcohol and phenolic solvents, slightly soluble in water. It is yellow in acidic solution and blue in alkaline solution.
Use:
3-BROMOBENZENE-1,2-DIOL is widely used in chemical analysis, biochemistry and biological experiments. The Main uses include the following:
1. Acid-base indicator: it can show different colors in acid-base solution, commonly used in acid-base titration, acid-base neutralization point determination.
2. DNA gel electrophoresis: It can be used as a nucleic acid dye in DNA gel electrophoresis to detect the size of DNA fragments.
3. Protein electrophoresis: It can also be used as a dye in protein electrophoresis for detection of protein separation and quantification.
4. Biological development: It can be used as a developer in biological imaging to detect the presence and quantification of biological molecules.
Method:
There are two main methods for preparing 3-BROMOBENZENE-1,2-DIOL:
1. Bromination reaction of nitrobenzene, and then reduction reaction to obtain 3-bromo O-aniline, and finally through oxidation reaction to obtain 3-BROMOBENZENE-1,2-DIOL.
2.3-BROMOBENZENE-1,2-DIOL was obtained by bromination of Catechol.
Safety Information:
3-BROMOBENZENE-1,2-DIOL is an organic compound with certain toxicity. Contact with skin, eyes and respiratory tract may cause irritation and burns, so wear appropriate protective equipment such as gloves and glasses when used. During use or storage, contact with strong oxidants, strong acids and other substances should be avoided to avoid dangerous reactions. In addition, care should be taken to avoid inhalation of its dust or solution, regular ventilation, to ensure good ventilation of the operating area. Such as accidental contact or misuse, should immediately clean the affected parts, and timely medical treatment.
Last Update：2024-04-10 22:41:03
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