3-Bromomethylbenzenesulfonamide

3-Bromomethylbenzenesulfonamide - Names and Identifiers

Name	3-(Bromomethyl)benzenesulfonamide
Synonyms	LogP 3-Bromomethylbenzenesulfonamide 3-(Bromomethyl)benzenesulfonamide 3-(broMoMethyl)benzene-1-sulfonaMide benzenesulfonamide, 3-(bromomethyl)- Benzenesulfonamide, 3-(bromomethyl)-
CAS	220798-52-7
InChI	InChI=1/C7H8BrNO2S/c8-5-6-2-1-3-7(4-6)12(9,10)11/h1-4H,5H2,(H2,9,10,11)

3-Bromomethylbenzenesulfonamide - Physico-chemical Properties

Molecular Formula	C7H8BrNO2S
Molar Mass	250.11
Density	1.691
Boling Point	402°C at 760 mmHg
Flash Point	196.9°C
Vapor Presure	1.13E-06mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.614

3-Bromomethylbenzenesulfonamide - Introduction

3-(Bromomethyl) benzensulfonamide is an organic compound with the chemical formula C7H7BrNO2S. It is a white crystalline solid that is readily soluble in solvents. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid
-Molecular weight: 249.1g/mol
-Melting point: 115-120 degrees Celsius
-Boiling Point: No data
-Solubility: Soluble in organic solvents such as chloroform, dichloromethane and ether. Low solubility in water.

Use:
- 3-(Bromomethyl)benzenesulfonamide is commonly used as a reagent in organic synthesis, especially as a protecting group or reaction intermediate.
-It can be used to synthesize compounds containing benzenesulfonamide protecting group, and protect other functional groups from accidental reactions in chemical reactions.

Method:
- 3-(Bromomethyl)benzenesulfonamide can be prepared by the reaction of benzenesulfonamide and methyl bromide. The reaction is typically carried out under basic conditions, for example in the presence of sodium hydroxide.
-The steps of the reaction are usually as follows:
1. Benzenesulfonamide and methyl bromide are added to the alcohol solvent.
2. Stir the reaction mixture under basic conditions and react for several hours.
3. Filtration gives a solid product, which can be further purified.

Safety Information:
- 3-(Bromomethyl)benzenesulfonamide needs to be handled safely when storing and handling.
-It may be harmful to the human body, so avoid contact with skin, eyes and inhalation of its dust during operation.
-Wear appropriate protective gloves, goggles and respiratory protection when used.
-Store in a dry, cool place away from fire and oxidizing agents.

Last Update：2024-04-10 22:29:15