Name | 3-Chloro-4-fluoroaniline |
Synonyms | AKOS BBS-00003577 Fluorochloroaniline 3-Chlor-4-fluoranilin LABOTEST-BB LTBB000779 3-CHLORO-4-FLUOROANILINE 3-Chloro-4-fluoroaniline 3-CHLORO-4-FLUOROBENZENAMINE 3-chloro-4-fluorobenzenamine 3-chloro-4-fluoro-benzenamin 3-CHLORO-4-FLUORO-PHENYLAMINE |
CAS | 367-21-5 |
EINECS | 206-682-8 |
InChI | InChI=1/C6H5ClFN/c7-5-2-1-4(9)3-6(5)8/h1-3H,9H2 |
InChIKey | YSEMCVGMNUUNRK-UHFFFAOYSA-N |
Molecular Formula | C6H5ClFN |
Molar Mass | 145.56 |
Density | 1,226 g/cm3 |
Melting Point | 42-44 °C (lit.) |
Boling Point | 227-228 °C (lit.) |
Flash Point | >230°F |
Water Solubility | 10 g/L (20 ºC) |
Solubility | 10g/l |
Vapor Presure | 0.01 hPa (20 °C) |
Appearance | Crystalline Solid |
Color | Beige to brown |
BRN | 1562786 |
pKa | 3.60±0.10(Predicted) |
PH | 7 (10g/l, H2O, 20℃) |
Storage Condition | Store below +30°C. |
Stability | Stable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates. May be air-sensitive. |
Refractive Index | 1,54-1,542 |
Physical and Chemical Properties | Melting point 42-47°C boiling point 230°C flash point 149°C water-soluble 10g/L (20°C) |
Use | Is an important intermediate in the synthesis of norfloxacin |
Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R33 - Danger of cumulative effects R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
UN IDs | UN 2811 6.1/PG 2 |
WGK Germany | 2 |
FLUKA BRAND F CODES | 9-23 |
TSCA | T |
HS Code | 29214210 |
Hazard Note | Irritant/Toxic |
Hazard Class | 6.1 |
Packing Group | III |
Toxicity | LD50 orally in Rabbit: 506 mg/kg |
chemical properties | white crystalline powder. Melting point 44 ℃(45-47 ℃), boiling point 227-228 ℃, flash point 149 ℃. |
use | an important intermediate for the synthesis of norfloxacin. is an important intermediate for the synthesis of norfloxacin |
production method | using o-dichlorobenzene as raw material, obtained by nitration of nitric acid and reduction of hydrogen. |
EPA chemical information | information provided by: ofmpub.epa.gov (external link) |