3-Carboxyphenylacetonitrile

3-Carboxyphenylacetonitrile - Names and Identifiers

Name	3-(CYANOMETHYL)BENZOIC ACID
Synonyms	25-50 g Ketoprofen EP Impurity H 3-Carboxyphenylacetonitrile m-(Cyanomethyl)benzoic acid 3-(CYANOMETHYL)BENZOIC ACID 3-(Cyanomethyl)benzoic acid benzoic acid, 3-(cyanomethyl)- Benzoic acid, 3-(cyanomethyl)- Ketoprofen Impurity 8(Ketoprofen EP Impurity H)
CAS	5689-33-8
InChI	InChI=1/C9H7NO2/c10-5-4-7-2-1-3-8(6-7)9(11)12/h1-3,6H,4H2,(H,11,12)

3-Carboxyphenylacetonitrile - Physico-chemical Properties

Molecular Formula	C9H7NO2
Molar Mass	161.16
Density	1.257±0.06 g/cm3(Predicted)
Melting Point	175-176℃ (ethanol, 25% )
Boling Point	371.6±25.0 °C(Predicted)
Flash Point	178.566°C
Solubility	DMSO, Methanol (Slightly)
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	White
pKa	4.04±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.58

3-Carboxyphenylacetonitrile - Introduction

3-(CYANOMETHYL)BENZOIC ACID is an organic compound with the chemical formula C9H7NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
3-(CYANOMETHYL)BENZOIC ACID is a colorless to light yellow crystalline powder with a special benzoic acid odor. It is insoluble in water at room temperature, but can be dissolved in organic solvents. It is a stable compound, but may decompose under high temperature or light.

Use:
3-(CYANOMETHYL)BENZOIC ACID is mainly used as an intermediate in organic synthesis. It is widely used in the synthesis of drugs, pesticides and dyes. In addition, it can also be used as a raw material for coatings and adhesive additives.

Preparation Method:
3-(CYANOMETHYL)BENZOIC ACID can be prepared by reacting 3-chloromethylbenzoic acid with sodium cyanide. During the reaction, the chloromethylbenzoic acid was dissolved in aqueous ammonia and then sodium cyanide solution was added. The reaction is continued and, by heating and stirring, the product is finally obtained.

Safety Information:
3-(CYANOMETHYL)BENZOIC ACID is relatively safe under normal operating conditions, the following matters still need to be noted:
-It may have an irritating effect on the eyes, skin and respiratory tract, so take appropriate protective measures when exposed, such as wearing protective glasses, gloves and masks.
-Avoid inhaling its dust or solution and ensure that the operating area is well ventilated.
-Pay attention to the risk of fire prevention and static electricity accumulation during handling and storage.
-Waste disposal shall comply with local regulations.

When using chemicals, be sure to follow the safety procedures and refer to the safety data form of the relevant material.

Last Update：2024-04-09 20:52:54