3-Chloro-2-hydroxy-5-nitropyridine

3-Chloro-2-hydroxy-5-nitropyridine - Names and Identifiers

Name	3-Chloro-2-hydroxy-5-nitropyridine
Synonyms	3-Chloro-5-nitro-2-pyridone 3-chloro-5-nitro-2-pyridinol 3-Chloro-5-nitropyridin-2-ol 3-CHLORO-5-NITRO-PYRIDIN-2-OL 2-HYDROXY-3-CHLORO-5-NITROPYRIDINE 3-CHLORO-2-HYDROXY-5-NITROPYRIDINE 3-Chloro-2-hydroxy-5-nitropyridine 2(1H)-Pyridinone, 3-chloro-5-nitro- 2-Hydroxy-3-Chloro-5-Methyl Pyridine
CAS	22353-38-4
InChI	InChI=1/C6H6ClNO/c1-4-2-5(7)6(9)8-3-4/h2-3H,1H3,(H,8,9)

3-Chloro-2-hydroxy-5-nitropyridine - Physico-chemical Properties

Molecular Formula	C5H3ClN2O3
Molar Mass	174.54
Density	1.61±0.1 g/cm3(Predicted)
Melting Point	187-189°
Boling Point	286.1±40.0 °C(Predicted)
Solubility	soluble in Methanol
Appearance	Solid
Color	White to Light yellow
pKa	6.58±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.572
MDL	MFCD06656618

3-Chloro-2-hydroxy-5-nitropyridine - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 2811 6.1 / PGIII
Hazard Class	IRRITANT

3-Chloro-2-hydroxy-5-nitropyridine - Introduction

Is an organic compound with the chemical formula C5H3ClN2O3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Yellow to orange-yellow crystalline solid.
-Solubility: It is soluble in some organic solvents, such as ethanol and dichloromethane, but insoluble in water.
-Melting point: Its melting point is between 100-102 ° C.

Use:
-Chemical synthesis: It is an important intermediate widely used in the synthesis of drugs and pesticides.
-Antibacterial activity: It also has certain antibacterial activity, so it can be used as one of the components of antibacterial agents.

Method:
It can be prepared by reacting pyridine carbamate with sodium nitrite to form 3-amino-2-hydroxy-5-nitropyridine, and then by chlorination of sulfuric acid chlorine.

Safety Information:
-It has a certain degree of toxicity, and care should be taken to avoid contact with skin and eyes.
-Use with appropriate protective equipment, such as lab gloves and goggles.
-Maintain good ventilation during use.
-Waste should be disposed of in accordance with local regulations.

Last Update：2024-04-09 20:49:11