3-Chloro-2-methoxyisonicotinaldehyde

3-Chloro-2-methoxyisonicotinaldehyde - Names and Identifiers

Name	3-chloro-2-methoxy-pyridine-4-carbaldehyde
Synonyms	3-CHLORO-4-FORMYL-2-METHOXYPYRIDINE 3-Chloro-4-formyl-2-methoxypyridine 3-Chloro-2-methoxyisonicotinaldehyde 3-chloro-2-methoxypyridine-4-carbaldehyde 3-chloro-2-methoxy-pyridine-4-carbaldehyde 3-Chloro-2-methoxy-4-pyridinecarboxaldehyde 4-PYRIDINECARBOXALDEHYDE, 3-CHLORO-2-METHOXY- 4-pyridinecarboxaldehyde, 3-chloro-2-methoxy-
CAS	885167-89-5
InChI	InChI=1/C7H6ClNO2/c1-11-7-6(8)5(4-10)2-3-9-7/h2-4H,1H3

3-Chloro-2-methoxyisonicotinaldehyde - Physico-chemical Properties

Molecular Formula	C7H6ClNO2
Molar Mass	171.58
Density	1.317
Boling Point	251℃
Flash Point	105℃
Vapor Presure	0.022mmHg at 25°C
pKa	-0.87±0.18(Predicted)
Storage Condition	2-8°C
Refractive Index	1.569

3-Chloro-2-methoxyisonicotinaldehyde - Introduction

It is an organic compound with the formula C7H6ClNO2. It is a yellow liquid with a special smell. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Yellow liquid
-Molecular weight: 173.58g/mol
-Melting Point:-4°C
-Boiling Point: 220-221°C
-Solubility: Soluble in organic solvents such as alcohols, ethers and ketones, insoluble in water.

Use:
As an important organic synthesis intermediate, it is widely used in pharmaceutical synthesis and pesticide synthesis. It can be used to synthesize compounds containing a pyridine structure, such as pyridone and pyridinic acid. It can also be used as an active ligand to participate in the construction of metal complexes.

Preparation Method:
can be prepared by the reaction of pyridine and 2-methoxy-3-chloro-4-formylaniline. First, pyridine is reacted with 2-methoxy-3-chloro-4-formylaniline under basic conditions to produce the target product. Then, the pure product is obtained by the steps of extraction, crystallization and purification.

Safety Information:
Avoid direct contact with skin and eyes, and avoid inhalation or ingestion. Wear suitable protective equipment such as lab gloves, safety glasses and protective face masks. In the process of operation to ensure good ventilation. If you accidentally touch or inhale this compound, please seek medical advice.

Last Update：2024-04-09 21:01:54