3-Chloro-4-bromofluorobenzene
1-Bromo-2-chloro-4-fluorobenzene
CAS: 110407-59-5
Molecular Formula: C6H3BrClF
3-Chloro-4-bromofluorobenzene - Names and Identifiers
| Name | 1-Bromo-2-chloro-4-fluorobenzene |
| Synonyms | 3-Chloro-4-bromofluorobenzene 2-Bromo-5-fluorochlorobenzene 2-CHLORO-4-FLUOROBROMOBENZENE 4-Bromo-3-chlorofluorobenzene 1-Bromo-2-chloro-4-fluorobenzene 1-BROMO-2-CHLORO-4-FLUOROBENZENE 4-BROMO-3-CHLORO-1-FLUOROBENZENE |
| CAS | 110407-59-5 |
| InChI | InChI=1/C6H3BrClF/c7-5-2-1-4(9)3-6(5)8/h1-3H |
| InChIKey | LEFQPBAWVJEIJS-UHFFFAOYSA-N |
3-Chloro-4-bromofluorobenzene - Physico-chemical Properties
| Molecular Formula | C6H3BrClF |
| Molar Mass | 209.44 |
| Density | 1.75 |
| Boling Point | 62-62.8 °C(Press: 12 Torr) |
| Flash Point | 72.5°C |
| Vapor Presure | 0.564mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.5525 |
3-Chloro-4-bromofluorobenzene - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37 - Wear suitable gloves. |
| HS Code | 29039990 |
| Hazard Note | Irritant |
3-Chloro-4-bromofluorobenzene - Introduction
1-bromo -2-chloro -4-fluorobenzene, chemical formula is C6H3BrClF, colorless liquid at room temperature. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1-Bromo-2-chloro-4-fluorobenzene is an organic halogen compound with special physical and chemical properties. Its boiling point is 50-52 degrees Celsius and its density is 1.756 g/ml. The compound is insoluble in water at normal temperature and soluble in organic solvents such as ethanol and dimethylformamide.
Use:
1-Bromo-2-chloro-4-fluorobenzene is an important intermediate compound, which is widely used in organic synthesis reactions. It can be used as a synthetic raw material for pesticides, drugs and dyes. In addition, it can also be used as an anti-aging agent and a light stabilizer for rubber products.
Preparation Method:
The preparation of 1-bromo-2-chloro-4-fluorobenzene is usually obtained by reacting acetylenic acetate with magnesium bromide. First, acetylenic acetate is reacted with magnesium bromide to obtain an alkynyl magnesium salt under heating, and then the alkynyl magnesium salt is reacted with hydrogen fluoride gas and ethyl chloride together to obtain 1-bromo-2-chloro-4-fluorobenzene.
Safety Information:
1-Bromo-2-chloro-4-fluorobenzene is an organic halogen compound with certain toxicity. Use the process should pay attention to protective measures, avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In addition, the compound should be protected from fire and high temperature during storage and transportation to prevent combustion or explosion accidents.
Nature:
1-Bromo-2-chloro-4-fluorobenzene is an organic halogen compound with special physical and chemical properties. Its boiling point is 50-52 degrees Celsius and its density is 1.756 g/ml. The compound is insoluble in water at normal temperature and soluble in organic solvents such as ethanol and dimethylformamide.
Use:
1-Bromo-2-chloro-4-fluorobenzene is an important intermediate compound, which is widely used in organic synthesis reactions. It can be used as a synthetic raw material for pesticides, drugs and dyes. In addition, it can also be used as an anti-aging agent and a light stabilizer for rubber products.
Preparation Method:
The preparation of 1-bromo-2-chloro-4-fluorobenzene is usually obtained by reacting acetylenic acetate with magnesium bromide. First, acetylenic acetate is reacted with magnesium bromide to obtain an alkynyl magnesium salt under heating, and then the alkynyl magnesium salt is reacted with hydrogen fluoride gas and ethyl chloride together to obtain 1-bromo-2-chloro-4-fluorobenzene.
Safety Information:
1-Bromo-2-chloro-4-fluorobenzene is an organic halogen compound with certain toxicity. Use the process should pay attention to protective measures, avoid contact with skin, eyes and respiratory tract. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In addition, the compound should be protected from fire and high temperature during storage and transportation to prevent combustion or explosion accidents.
Last Update：2024-04-09 21:01:54
