3-Chloro-4-methoxy-carbonitrile

3-Chloro-4-methoxy-carbonitrile - Names and Identifiers

Name	3-Chloro-4-methoxybenzonitrile
Synonyms	3-Chloro-4-methoxybenzonitrile 3-CHLORO-4-METHOXYBENZONITRILE 3-Chloro-4-Methoxybenzonitrile 3-Chloro-4-methoxy-carbonitrile 3-CHLORO-4-METHOXYBENZONITRILE v Benzonitrile, 3-chloro-4-methoxy-
CAS	102151-33-7
EINECS	625-164-6
InChI	InChI=1/C8H6ClNO/c1-11-8-3-2-6(5-10)4-7(8)9/h2-4H,1H3

3-Chloro-4-methoxy-carbonitrile - Physico-chemical Properties

Molecular Formula	C8H6ClNO
Molar Mass	167.59
Density	1.25g/cm³
Melting Point	107-111 °C (lit.)
Boling Point	265.7°C at 760 mmHg
Flash Point	114.5°C
Vapor Presure	0.00903mmHg at 25°C
BRN	5926726
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.548
MDL	MFCD03093073

3-Chloro-4-methoxy-carbonitrile - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
UN IDs	3276
WGK Germany	3
Hazard Class	6.1
Packing Group	III

3-Chloro-4-methoxy-carbonitrile - Introduction

3-Chloro-4-methoxybenzonitrile is an organic compound with the chemical formula C8H6ClNO. The following is an introduction to some of its properties, uses, methods and safety information:

Properties: 3-Chloro-4-methoxybenzonitrile is a colorless or light yellow solid with an odor similar to benzonitrile. It has a melting point of 50-53 degrees Celsius and a boiling point of 305 degrees Celsius. It is almost insoluble in water at normal temperature, but soluble in organic solvents such as alcohols, ethers and ketones.

Uses: 3-Chloro-4-methoxybenzonitrile is mainly used as an intermediate in organic synthesis. It has a wide range of applications in the field of medicine, pesticides and dyes. For example, it can be used to synthesize some biologically active compounds as precursors or intermediates of drugs. In addition, it can also be used as a raw material for dyes, for the preparation of pigments and organic dyes.

Preparation method: 3-chloro-4-methoxybenzonitrile can be prepared by an oxidation reaction of benzonitrile and ferric chloride. The reaction conditions may be that benzonitrile is reacted with ferric chloride by heating in an appropriate solvent, usually at a reaction temperature of 40-50 degrees Celsius for a longer reaction time.

Safety information: 3-Chloro-4-methoxybenzonitrile has certain toxicity, and safety should be paid attention to when using it. Avoid contact with skin, eyes and respiratory tract, and wear appropriate personal protective equipment such as chemical protective gloves, goggles and protective masks during operation. During storage and use, it should be kept away from fire and oxidizing agents, and properly kept in a closed container. If splashed into the eyes or skin, should immediately rinse with plenty of water, and timely medical treatment. Local environmental laws and regulations should be followed when disposing of waste.

Last Update：2024-04-09 20:52:54