3-Chloropyrazin-2-amine
2-Amino-3-chloropyrazine
CAS: 6863-73-6;6663-73-6
Molecular Formula: C4H4ClN3
3-Chloropyrazin-2-amine - Names and Identifiers
| Name | 2-Amino-3-chloropyrazine |
| Synonyms | TIMTEC-BB SBB006510 3-Chloropyrazin-2-amine 3-Chloro-2-pyrazinamine 3-AMINO-PYRAZINECHLORIDE 2-CHLORO-3-AMINEPYRAZINE 2-AMINO-3-CHLOROPYRAZINE 2-Amino-3-chloropyrazine 2-PyrazinaMine, 3-chloro- 3-AMINO-2-CHLORO-PYRAZINE 2-Pyrazinamine, 3-chloro- 3-Chloro-pyrazin-2-ylaMine |
| CAS | 6863-73-6 6663-73-6 |
| InChI | InChI=1/C4H4ClN3/c5-3-4(6)8-2-1-7-3/h1-2H,(H2,6,8) |
| InChIKey | AEVSSZHXGJAPIE-UHFFFAOYSA-N |
3-Chloropyrazin-2-amine - Physico-chemical Properties
| Molecular Formula | C4H4ClN3 |
| Molar Mass | 129.55 |
| Density | 1.437±0.06 g/cm3(Predicted) |
| Melting Point | 164-169°C |
| Boling Point | 248.1±35.0 °C(Predicted) |
| Flash Point | 103.8°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.0248mmHg at 25°C |
| pKa | 2.37±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.617 |
| MDL | MFCD04114305 |
3-Chloropyrazin-2-amine - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 1 |
| HS Code | 29339900 |
| Hazard Note | Irritant |
| Hazard Class | IRRITANT |
3-Chloropyrazin-2-amine - Introduction
2-Amino-3-chroopyrazine (2-Amino-3-chroopyrazine) is an organic compound. Its chemical formula is C4H4ClN3, with the presence of one amino group and one chlorine atom.
2-Amino-3-chloroopyrazine is a colorless solid at room temperature and can be dissolved in some organic solvents such as ethanol and dimethylformamide. Its melting point is about 120-121°C.
In the field of chemistry, 2-Amino-3-chlorine can be used as an intermediate in organic synthesis. It can participate in a variety of reactions, such as aromatic substitution reactions, condensation reactions, etc., for the synthesis of various organic compounds. In addition, it can also be used as raw materials in the fields of dyes and medicine.
A common method for preparing 2-Amino-3-chloropyrazine is through the reaction of 2,3-pyrazinedione and carbamate under the catalysis of hydrochloric acid. First, the 2,3-pyrazinedione and the carbamate are mixed and heated to react. When the reaction is carried out, attention should be paid to controlling the reaction temperature and reaction time to obtain a good yield. Finally, the pure 2-Amino-3-chlorine product can be obtained by crystallization or other separation and purification methods.
Pay attention to safety when using 2-Amino-3-chlorine. It can cause irritation to the eyes and skin, so wear appropriate protective measures during use, such as gloves, goggles, etc. When storing and handling the compound, care should be taken to avoid contact with open flames and oxidizing agents. In addition, it should be stored in a dry, cool place, away from fire and flammable substances.
2-Amino-3-chloroopyrazine is a colorless solid at room temperature and can be dissolved in some organic solvents such as ethanol and dimethylformamide. Its melting point is about 120-121°C.
In the field of chemistry, 2-Amino-3-chlorine can be used as an intermediate in organic synthesis. It can participate in a variety of reactions, such as aromatic substitution reactions, condensation reactions, etc., for the synthesis of various organic compounds. In addition, it can also be used as raw materials in the fields of dyes and medicine.
A common method for preparing 2-Amino-3-chloropyrazine is through the reaction of 2,3-pyrazinedione and carbamate under the catalysis of hydrochloric acid. First, the 2,3-pyrazinedione and the carbamate are mixed and heated to react. When the reaction is carried out, attention should be paid to controlling the reaction temperature and reaction time to obtain a good yield. Finally, the pure 2-Amino-3-chlorine product can be obtained by crystallization or other separation and purification methods.
Pay attention to safety when using 2-Amino-3-chlorine. It can cause irritation to the eyes and skin, so wear appropriate protective measures during use, such as gloves, goggles, etc. When storing and handling the compound, care should be taken to avoid contact with open flames and oxidizing agents. In addition, it should be stored in a dry, cool place, away from fire and flammable substances.
Last Update：2024-04-09 21:01:54
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