3-Chloropyridine-2-carboxaldehyde

3-Chloropyridine-2-carboxaldehyde - Names and Identifiers

Name	3-chloropyridine-2-carbaldehyde
Synonyms	LogP 3-chloropicolinaldehyde 3-Chloro-2-formylpyridine 3-Chloropyridine-2-carbaldehyde 3-chloropyridine-4-carbaldehyde 3-chloropyridine-2-carbaldehyde 3-Chloropyridine-2-carboxaldehyde 3-chloro-2-Pyridinecarboxaldehyde 2-Pyridinecarboxaldehyde, 3-chloro- 2-pyridinecarboxaldehyde, 3-chloro- 2-Pyridinecarboxaldehyde,3-chloro-(9CI)
CAS	206181-90-0
InChI	InChI=1/C6H4ClNO/c7-5-2-1-3-8-6(5)4-9/h1-4H

3-Chloropyridine-2-carboxaldehyde - Physico-chemical Properties

Molecular Formula	C6H4ClNO
Molar Mass	141.56
Density	1.332
Boling Point	202℃
Flash Point	76℃
Vapor Presure	0.306mmHg at 25°C
pKa	1.12±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.593

3-Chloropyridine-2-carboxaldehyde - Introduction

It is an organic compound whose structural formula is C5H4ClNO. The following is a detailed introduction about Lin:

Nature:
1. Appearance: White crystalline powder.
2. Solubility: solubility in water is low, soluble in organic solvents such as chloroform, ethanol, etc.
3. Stability: relatively stable at room temperature, but easy to decompose when encountering strong acid or alkali.

Use:
1. Antibacterial agent: it has strong antibacterial activity and can be used to prepare antibacterial drugs, disinfectants, etc.
2. Medicine field: because of its antibacterial properties, it is widely used in the field of medicine, such as the preparation of oral health products, external medicine, etc.

Method:
Preparation can be carried out by the following steps:
1. Pyridine is reacted with chloroform in acetic acid.
2. Add hydrogen chloride and sodium nitrite to react to obtain 3-chloropyridine-2-aldehyde.
3. Finally, it is obtained by crystallization and purification.

Safety Information:
1. Is an organic compound, may be toxic to the human body, please pay attention to avoid contact with skin, eyes and respiratory tract.
2. In use or storage, please avoid contact with strong acid, strong alkali and oxidizing agent to prevent chemical reaction.
3. In case of inhalation or contact, rinse the affected area immediately with plenty of water and seek medical attention as soon as possible.
4. During use, please wear appropriate protective equipment, such as laboratory gloves and glasses, to ensure safety.

Last Update：2024-04-09 15:17:55