3-Chloropyridine-4-carbonitrile

3-Chloropyridine-4-carbonitrile - Names and Identifiers

Name	3-Chloro-4-cyanopyridine
Synonyms	3-Chloro-4-cyanopyri 3-chloro-4-cynopyridine 3-CHLORO-4-CYANOPYRIDINE 3-Chloro-4-cyanopyridine 3-CHLORO-ISONICOTINONITRILE 3-Chloropyridine-4-carbonitrile 3-Chloro-4-pyridinecarbonitrile 3-CHLOROPYRIDINE-4-CARBONITRILE 4-Pyridinecarbonitrile,3-chloro-(9CI)
CAS	68325-15-5
InChI	InChI=1/C6H3ClN2/c7-6-4-9-2-1-5(6)3-8/h1-2,4H
InChIKey	JLLJPPBGJVCFGG-UHFFFAOYSA-N

3-Chloropyridine-4-carbonitrile - Physico-chemical Properties

Molecular Formula	C6H3ClN2
Molar Mass	138.55
Density	1.33±0.1 g/cm3(Predicted)
Melting Point	71-73°C
Boling Point	233.3±20.0 °C(Predicted)
Flash Point	94.899°C
Solubility	Dichloromethane, Ethyl Acetate, Methanol
Vapor Presure	0.056mmHg at 25°C
Appearance	Solid
Color	Pale Yellow
pKa	-0.41±0.18(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.566
MDL	MFCD05663706

3-Chloropyridine-4-carbonitrile - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
UN IDs	UN3439
WGK Germany	3
HS Code	29333990
Hazard Note	Irritant
Hazard Class	6.1
Packing Group	III

3-Chloropyridine-4-carbonitrile - Introduction

3-Chloro-4-cyanopyridine(3-Chloro-4-cyanopyridine) is an organic compound. The following is a brief description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless crystalline or white solid.
-Molecular formula: C6H3ClN2.
-Molecular weight: 138.56g/mol.
-Melting point: 76-78 degrees Celsius.
-Boiling point: 297 degrees Celsius.
-Soluble in some organic solvents at room temperature, such as ethanol and ether.

Use:
- 3-Chloro-4-cyanopyridine can be used as an important intermediate in organic synthesis.
-It can be used to prepare some drugs in the field of medicine, such as pyrimidine compounds and nifedipine.
-The compound can also be used in the synthesis of pesticides and dyes.

Preparation Method:
- 3-Chloro-4-cyanopyridine is generally obtained by cyanation of 3-chloropyridine.
-The cyanation reaction can be promoted by using commonly used cyanating reagents such as silver cyanide, sodium cyanide or potassium cyanide.

Safety Information:
- 3-Chloro-4-cyanopyridine is generally considered toxic and may cause certain harm to the human body.
-Avoid inhalation or contact with skin, eyes or respiratory system.
-Wear appropriate protective equipment such as gloves, glasses, and protective masks when using or handling the compound.
-The compound must not be released into the natural environment. Follow appropriate environmental measures when disposing of waste.
-When storing, place 3-Chloro-4-cyanopyridine in a dry, cool and well-ventilated place, away from sources of ignition or oxidizing agents.

Last Update：2024-04-09 02:00:47