3-Fluoro-4-cyanopyridine
2-fluoro-3-cyanopyridine
CAS: 3939-13-7
Molecular Formula: C6H3FN2
3-Fluoro-4-cyanopyridine - Names and Identifiers
| Name | 2-fluoro-3-cyanopyridine |
| Synonyms | 2-fluoronicotinonitrile 2-Fluoronicotinonitrile 3-Cyano-2-fluoropyridine 3-CYANO-2-FLUOROPYRIDINE 2-fluoro-nicotinonitrile 2-FLUORO-3-CYANOPYRIDINE 3-Cyano-4-fluoropyridine 2-fluoro-3-cyanopyridine 3-Fluoro-4-cyanopyridine 4-Fluoro-nicotinonitrile 2-FLUOROPYRIDINE-3-CARBONITRILE 2-fluoropyridine-3-carbonitrile 2-FLUORO-3-PYRIDINECARBONITRILE |
| CAS | 3939-13-7 |
| EINECS | 678-765-0 |
| InChI | InChI=1/C6H3FN2/c7-6-5(4-8)2-1-3-9-6/h1-3H |
| InChIKey | USIDQCCXMGJOJM-UHFFFAOYSA-N |
3-Fluoro-4-cyanopyridine - Physico-chemical Properties
| Molecular Formula | C6H3FN2 |
| Molar Mass | 122.1 |
| Density | 1.24±0.1 g/cm3(Predicted) |
| Melting Point | 27-30°C |
| Boling Point | 214.6±20.0 °C(Predicted) |
| Flash Point | 98℃ |
| Vapor Presure | 0.154mmHg at 25°C |
| BRN | 386567 |
| pKa | -3.88±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.509 |
3-Fluoro-4-cyanopyridine - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R5 - Heating may cause an explosion R36/38 - Irritating to eyes and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. S23 - Do not breathe vapour. S3 - Keep in a cool place. |
| UN IDs | 3276 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Harmful/Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
3-Fluoro-4-cyanopyridine - Introduction
Nature:
-Appearance: 2-fluoro-3-cyanopyridine is a colorless to light yellow crystalline solid.
-Solubility: It is soluble in organic solvents such as ethanol, ether and chloroform, and slightly soluble in water.
Use:
- 2-fluoro-3-cyanopyridine is widely used as an intermediate in organic synthesis. It can be used to synthesize a variety of organic compounds, such as pharmaceuticals, pesticides and dyes.
Preparation Method:
The preparation method of-2-fluoro-3-cyanopyridine is generally chemical synthesis. A common preparation method is to react pyridine with fluorine gas to obtain 2-fluoropyridine, which is then reacted with cyano group under acidic conditions to form 2-fluororo-3-cyanopyridine.
Safety Information:
- 2-fluoro-3-cyanopyridine is a chemical that should be used in a laboratory environment and follow relevant safety operating guidelines.
-It may have an irritating effect on the eyes, skin and respiratory system and requires attention to protective measures.
-Avoid contact with fire sources during handling or storage to prevent fire or explosion.
-Avoid inhaling gas or dust when using, and ensure adequate ventilation.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 19:05:49
