3-Fluoro-4-methoxybenzylcyanide

3-Fluoro-4-methoxybenzylcyanide - Names and Identifiers

Name	3-fluoro-4-methoxyphenylacetonitrile
Synonyms	3-Fluoro-4-methoxybenzylcyanide 4-(Cyanomethyl)-2-fluoroanisole 3-FLUORO-4-METHOXYBENZYL CYANIDE 3-FLUORO-4-METHOXYPHENYLACETONITRILE 3-fluoro-4-methoxyphenylacetonitrile 3-Fluoro-4-methoxyphenylacetonitrile Benzeneacetonitrile, 3-fluoro-4-Methoxy- 2-(3-fluoro-4-methoxyphenyl)acetonitrile 2-(3-fluoro-4-methoxy-phenyl)acetonitrile 2-(3-fluoro-4-methoxy-phenyl)ethanenitrile
CAS	404-90-0
InChI	InChI=1/C9H8FNO/c1-12-9-3-2-7(4-5-11)6-8(9)10/h2-3,6H,4H2,1H3

3-Fluoro-4-methoxybenzylcyanide - Physico-chemical Properties

Molecular Formula	C9H8FNO
Molar Mass	165.16
Density	1.148±0.06 g/cm3(Predicted)
Melting Point	46-48°C
Boling Point	99-105 °C(Press: 0.5 Torr)
Flash Point	117.5°C
Vapor Presure	0.00676mmHg at 25°C
Appearance	Yellow-like crystals
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.501
MDL	MFCD00040889

3-Fluoro-4-methoxybenzylcyanide - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3439
Hazard Note	Irritant
Hazard Class	6.1
Packing Group	III

3-Fluoro-4-methoxybenzylcyanide - Introduction

It is an organic compound with the chemical formula C9H8FNO. Its structure contains a fluorine atom, a methoxy group and a nitrile group. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless or light yellow solid
-Melting point: about 40-42 degrees Celsius
-Boiling point: about 255-256 degrees Celsius
-Solubility: Soluble in some organic solvents, such as methanol, ethanol and dichloromethane

Use:
It can be used as an intermediate in organic synthesis, and is mainly used to prepare other compounds, such as drugs and pesticides. It has a certain activity and can participate in various reaction types, such as nucleophilic substitution and coupling reactions.

Preparation Method:
The preparation method can be achieved through the following steps:
1. At low temperature, 3-fluoro-4-methoxybenzeneacetaldehyde and sodium cyanide are reacted in a solvent.
2. After the reaction is completed, hydrolyze the nitrile group under acidic conditions (such as hydrochloric acid) to obtain the nitrile group.

Safety Information:
Toxicity and low risk, but still need to pay attention to the following aspects:
-Avoid contact with skin, eyes and mucous membranes.
-When using, should wear protective gloves and glasses.
-After operation or contact, the contaminated clothing should be thoroughly cleaned.
-When stored, it should be sealed and stored to avoid contact with oxidants and strong acids.
-Do not use in food, medicine or cosmetics.

Please note that the above information is for reference. Please refer to the relevant safety information of chemicals for specific operations.

Last Update：2024-04-09 15:17:57