3-Hydroxy-2-nitro-6-picoline

3-Hydroxy-2-nitro-6-picoline - Names and Identifiers

Name	6-methyl-2-nitropyridin-3-ol
Synonyms	6-Methyl-2-nitropyridin-3-ol 3-Hydroxy-2-nitro-6-picoline 6-METHYL-2-NITRO-3-PYRIDINOL 6-methyl-2-nitropyridin-3-ol 3-Pyridinol, 6-methyl-2-nitro- 3-HYDROXY-6-METHYL-2-NITROPYRIDINE 5-HYDROXY-2-METHYL-6-NITROPYRIDINE 6-METHYL-2-NITRO-3-HYDROXYPYRIDINE 3-Hydroxy-6-methyl-2-nitropyridine,6-Methyl-2-nitro-3-pyridinol
CAS	15128-90-2
EINECS	239-192-8
InChI	InChI=1/C6H6N2O3/c1-4-2-3-5(9)6(7-4)8(10)11/h2-3,9H,1H3
InChIKey	WZMGQHIBXUAYGS-UHFFFAOYSA-N

3-Hydroxy-2-nitro-6-picoline - Physico-chemical Properties

Molecular Formula	C6H6N2O3
Molar Mass	154.12
Density	1.4564 (rough estimate)
Melting Point	106-107 °C (lit.)
Boling Point	277.46°C (rough estimate)
Flash Point	177.8°C
Vapor Presure	5.2E-06mmHg at 25°C
Appearance	Yellow fine crystalline powder
BRN	974751
pKa	1.01±0.22(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.5100 (estimate)
MDL	MFCD00006259

3-Hydroxy-2-nitro-6-picoline - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing.
WGK Germany	3

3-Hydroxy-2-nitro-6-picoline - Introduction

6-methyll-2-nitropyridin-3-ol is an organic compound with the chemical formula C7H7NO3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 6-methyll-2-nitropyridin-3-ol is a pale yellow solid.
-Melting point: The melting point range is 75-77°C.
-Solubility: Slightly soluble in water, soluble in some organic solvents such as ethanol, acetone and dichloromethane.

Use:
-6-methyll-2-nitropyridin-3-ol is commonly used in the synthesis of organic compounds such as pharmaceuticals and pesticides.
-It can be used as an intermediate to participate in a variety of chemical reactions, such as oxidation, reduction, substitution, etc.

Method:
-6-methyll-2-nitropyridin-3-ol has many preparation methods, and common methods include Nitro reaction and amination reaction.
The method of-Nitro reaction is to react 3-hydroxy-6-methylpyridine with nitric acid under appropriate conditions, such as under acidic conditions, to obtain the target product.
-The method of the amination reaction is to react 3-hydroxy-6-methylpyridine with hydrophilic Amine, using an appropriate catalyst and reaction temperature to obtain the target product.

Safety Information:
-6-methyll-2-nitropyridin-3-ol should pay attention to safety protection measures during use, such as wearing protective gloves and goggles.
-It may have an irritating effect on the skin, eyes and respiratory tract, so direct contact should be avoided.
-During operation and storage, keep away from ignition and flammable materials.
-If accidentally splashed into the eyes or inhaled during use, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 20:49:11