3-Hydroxypyridine-2-carboxaldehyde - Names and Identifiers
3-Hydroxypyridine-2-carboxaldehyde - Physico-chemical Properties
Molecular Formula | C6H5NO2
|
Molar Mass | 123.11 |
Density | 1.327±0.06 g/cm3(Predicted) |
Melting Point | 80-82°C (subl.) |
Boling Point | 96-100°C/30mm |
Flash Point | 130.6°C |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Vapor Presure | 0.00106mmHg at 25°C |
Appearance | Solid |
Color | Dark Brown |
pKa | pK1:3.40(+1);pK2:6.95(OH)(20°C) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.629 |
3-Hydroxypyridine-2-carboxaldehyde - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
Hazard Class | IRRITANT |
3-Hydroxypyridine-2-carboxaldehyde - Introduction
It is an organic compound with a chemical formula of C7H7NO2 and a molecular weight of 137.14g/mol. The following is a description of its nature, use, preparation and safety information:
Nature:
It is a colorless to light yellow solid with a special pyridine odor. It is soluble in water and some organic solvents such as alcohols, ethers and chloroform. It is stable at room temperature, but will decompose under high temperature or ultraviolet light.
Use:
It is widely used in organic synthesis. It is an important intermediate for the synthesis of pyridine compounds, which can be used to prepare drugs, pesticides, dyes and photosensitizers. In addition, it can also be used as a functional additive such as a light stabilizer, a light curing agent and an amine releasing agent.
Method:
Ni can be prepared by the oxidation reaction of 2-pyridyl methanol with an oxidizing agent. A common method is to dissolve 2-pyridyl methanol in a strong oxidizing acid, such as concentrated nitric acid or concentrated sulfuric acid, and heat to the reaction temperature. Subsequently, the reaction is diluted, cooled, and washed and neutralized with water or base to give the product.
Safety Information:
It is an organic compound that is corrosive and irritating. During operation, attention should be paid to avoid direct contact with skin, eyes and respiratory tract, and strengthen ventilation protection. During handling and storage, it should be kept in a cool, dry, well-ventilated place, away from fire and oxidizing agents. In addition, avoid mixing with strong oxidants and reducing agents. In the event of inadvertent contact or inhalation, wash the affected area immediately and seek medical help.
Last Update:2024-04-09 20:52:54