3-Iodo-4-hydroxypyridine - Names and Identifiers
3-Iodo-4-hydroxypyridine - Physico-chemical Properties
Molecular Formula | C5H4INO
|
Molar Mass | 221 |
Density | 2.142±0.06 g/cm3(Predicted) |
Melting Point | 303 °C(Solv: water (7732-18-5)) |
Boling Point | 336.1±22.0 °C(Predicted) |
Flash Point | 113.1°C |
Vapor Presure | 0.0103mmHg at 25°C |
pKa | 3.79±0.18(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.682 |
3-Iodo-4-hydroxypyridine - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
Hazard Class | IRRITANT |
3-Iodo-4-hydroxypyridine - Introduction
3-iodopyridin-4(1H)-one, also known as 3-iodopyridin-4(1H)-one, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
1. nature:
-Appearance: 3-iodopyridin-4(1H)-one is usually yellow crystals or powder.
-Melting point: about 100-105°C.
-Solubility: Soluble in most organic solvents, such as ethanol, chloroform and dimethyl sulfoxide.
2. use:
-Chemical reagents: commonly used in organic synthesis reactions as raw materials or intermediates.
-Drug synthesis: It can be used to prepare 3-iodopyridine-4-ketone compounds, which have potential application value in drug synthesis.
3. preparation method:
Commonly used preparation methods include the following ways:
-3-Carbonate is obtained by the reaction of 3-iodopyridine and sodium carbonate.
-3-Carbonate reacts with acid to form a salt of 3-carbonic acid hydrochloric acid.
-3-iodopyridin-4(1H)-one is obtained by acidification, neutralization and dehydration.
4. Safety Information:
- 3-iodopyridin-4(1H)-one has limited information on toxicity, so it is necessary to follow general laboratory safety procedures during use.
-Avoid inhalation, skin contact or ingestion, and wear appropriate protective equipment.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-should be stored in a dry, cool place, away from combustibles and oxidants.
Please note that the information provided above is for reference only, and the specific operation and use should be based on the actual situation and relevant scientific literature.
Last Update:2024-04-09 20:49:11