3-Methoxy-pyridin-4-ylamine
3-methoxypyridin-4-amine
CAS: 52334-90-4
Molecular Formula: C6H8N2O
3-Methoxy-pyridin-4-ylamine - Names and Identifiers
| Name | 3-methoxypyridin-4-amine |
| Synonyms | 3-Methoxy-4-PyridinaMine 3-methoxypyridin-4-amine 3-Methoxypyridin-4-amine 3-methoxy-4-aminopyridine 4-Amino-3-methoxypyridine 4-Pyridinamine, 3-methoxy- 4-pyridinamine, 3-methoxy- 3-Methoxy-pyridin-4-ylamine |
| CAS | 52334-90-4 |
| EINECS | 214-589-6 |
| InChI | InChI=1/C6H8N2O/c1-9-6-4-8-3-2-5(6)7/h2-4H,1H3,(H2,7,8) |
3-Methoxy-pyridin-4-ylamine - Physico-chemical Properties
| Molecular Formula | C6H8N2O |
| Molar Mass | 124.14 |
| Density | 1.139±0.06 g/cm3(Predicted) |
| Melting Point | 94.5-95.5 °C |
| Boling Point | 277.8±20.0 °C(Predicted) |
| Flash Point | 121.8°C |
| Vapor Presure | 0.00442mmHg at 25°C |
| pKa | 8.11±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.56 |
3-Methoxy-pyridin-4-ylamine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
3-Methoxy-pyridin-4-ylamine - Introduction
3-methoxypyridin-4-amine is an organic compound with the chemical formula C6H8N2O. Its properties are as follows:
1. Appearance: 3-methoxypyridin-4-amine is a white solid.
2. Solubility: It has low solubility in water, but it can be dissolved in common organic solvents such as ethanol and dimethylformamide.
Use of 3-methoxypyridin-4-amine:
1. Chemical intermediate: It is used as an intermediate for the synthesis of other organic compounds and is commonly used in the synthesis of drugs and pesticides.
2. Catalyst: It can be used as a catalyst for oxidation reactions.
Preparation Method:
The preparation method of 3-methoxypyridin-4-amine is usually achieved by electrophilic substitution of pyridine. First, pyridine is reacted with ethyl bromide to form N-ethylpyridine. The N-ethylpyridine is then reacted with methanol to produce 3-methoxypyridine. Finally, 3-methoxypyridin-4-amine is reacted with ammonia to give 3-methoxypyridin-4-amine.
Safety Information:
The specific safety information about 3-methoxypyridin-4-amine should be evaluated according to its specific application and operating conditions. In general, chemicals should be handled carefully, avoid direct contact with skin and eyes, and maintain a well-ventilated operating environment. Proper laboratory practices and safe operating procedures should be followed when using chemicals. For more detailed safety information, please refer to the relevant chemical safety data sheet (Material Safety Data Sheet, MSDS) or consult a chemical professional.
1. Appearance: 3-methoxypyridin-4-amine is a white solid.
2. Solubility: It has low solubility in water, but it can be dissolved in common organic solvents such as ethanol and dimethylformamide.
Use of 3-methoxypyridin-4-amine:
1. Chemical intermediate: It is used as an intermediate for the synthesis of other organic compounds and is commonly used in the synthesis of drugs and pesticides.
2. Catalyst: It can be used as a catalyst for oxidation reactions.
Preparation Method:
The preparation method of 3-methoxypyridin-4-amine is usually achieved by electrophilic substitution of pyridine. First, pyridine is reacted with ethyl bromide to form N-ethylpyridine. The N-ethylpyridine is then reacted with methanol to produce 3-methoxypyridine. Finally, 3-methoxypyridin-4-amine is reacted with ammonia to give 3-methoxypyridin-4-amine.
Safety Information:
The specific safety information about 3-methoxypyridin-4-amine should be evaluated according to its specific application and operating conditions. In general, chemicals should be handled carefully, avoid direct contact with skin and eyes, and maintain a well-ventilated operating environment. Proper laboratory practices and safe operating procedures should be followed when using chemicals. For more detailed safety information, please refer to the relevant chemical safety data sheet (Material Safety Data Sheet, MSDS) or consult a chemical professional.
Last Update：2024-04-09 21:54:55
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