3-Methyl-1-(1-methyl-4-piperidinyl)-1H-pyrazol-5-amine
5-Methyl-2-(1-methyl-piperidin-4-yl)-2H-pyrazol-3-ylamine
CAS: 3524-43-4
Molecular Formula: C10H18N4
3-Methyl-1-(1-methyl-4-piperidinyl)-1H-pyrazol-5-amine - Names and Identifiers
3-Methyl-1-(1-methyl-4-piperidinyl)-1H-pyrazol-5-amine - Physico-chemical Properties
| Molecular Formula | C10H18N4 |
| Molar Mass | 194.28 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD03627790 |
3-Methyl-1-(1-methyl-4-piperidinyl)-1H-pyrazol-5-amine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
3-Methyl-1-(1-methyl-4-piperidinyl)-1H-pyrazol-5-amine - Introduction
3-Methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine is an organic compound with the chemical formula C12H19N5. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine is a white to light yellow crystalline powder.
-Melting point: about 165-168 ℃.
-Solubility: 3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine is soluble in some organic solvents such as dichloromethane and ethanol.
Use:
- 3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine is commonly used as a pharmaceutical intermediate and can be used to synthesize various biologically active compounds.
-It is widely used in the field of medicine and can be used to prepare anti-inflammatory, analgesic and anti-cancer drugs.
Preparation Method:
3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine can be prepared by two methods:
-Reduction of the phenylacetone derivative by hydrogenation: First, the phenylacetone derivative is reacted with methylpiperidine to obtain an intermediate, and then a reduction reaction is performed to generate the target compound.
-Through the benzyl derivative of pyrazol-5-amine: First synthesize the benzyl derivative of pyrazol-5-amine through a condensation reaction under alkaline conditions, and then perform an N-methylation reaction to generate the target compound.
Safety Information:
3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine has limited safety information, so it is important to follow laboratory safety practices when using this compound and take appropriate personal protective measures. It may be irritating to the eyes, skin and respiratory system, so contact must be avoided. Wear appropriate protective gloves, goggles, and respiratory protective equipment when handling this compound. At the same time, store it in a dry, cool place, away from fire and oxidizing agents.
Nature:
-Appearance: 3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine is a white to light yellow crystalline powder.
-Melting point: about 165-168 ℃.
-Solubility: 3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine is soluble in some organic solvents such as dichloromethane and ethanol.
Use:
- 3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine is commonly used as a pharmaceutical intermediate and can be used to synthesize various biologically active compounds.
-It is widely used in the field of medicine and can be used to prepare anti-inflammatory, analgesic and anti-cancer drugs.
Preparation Method:
3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine can be prepared by two methods:
-Reduction of the phenylacetone derivative by hydrogenation: First, the phenylacetone derivative is reacted with methylpiperidine to obtain an intermediate, and then a reduction reaction is performed to generate the target compound.
-Through the benzyl derivative of pyrazol-5-amine: First synthesize the benzyl derivative of pyrazol-5-amine through a condensation reaction under alkaline conditions, and then perform an N-methylation reaction to generate the target compound.
Safety Information:
3-methyl -1-(1-methylpiperidin-4-yl)-1H-pyrazol-5-amine has limited safety information, so it is important to follow laboratory safety practices when using this compound and take appropriate personal protective measures. It may be irritating to the eyes, skin and respiratory system, so contact must be avoided. Wear appropriate protective gloves, goggles, and respiratory protective equipment when handling this compound. At the same time, store it in a dry, cool place, away from fire and oxidizing agents.
Last Update：2024-04-09 21:11:58
