3-Methyl-3-phenoxyazetidine
3-Methyl-3-phenoxyazetidine HCl
CAS: 1323362-91-9
Molecular Formula: C10H13NO
3-Methyl-3-phenoxyazetidine - Names and Identifiers
| Name | 3-Methyl-3-phenoxyazetidine HCl |
| Synonyms | 3-Methyl-3-phenoxyazetidine Azetidine, 3-methyl-3-phenoxy- 3-Methyl-3-phenoxyazetidine HCl 3-Methyl-3-phenoxyazetidinehydrochloride |
| CAS | 1323362-91-9 |
3-Methyl-3-phenoxyazetidine - Physico-chemical Properties
| Molecular Formula | C10H13NO |
| Molar Mass | 163.22 |
| Density | 1.053±0.06 g/cm3(Predicted) |
| Boling Point | 241.6±33.0 °C(Predicted) |
| pKa | 9.20±0.40(Predicted) |
3-Methyl-3-phenoxyazetidine - Introduction
3-Methyl-3-phenoxyazetidine hydrochloride, chemical formula C16H17NO • HCl, is an organic compound with the following properties:
1. Appearance: white crystalline solid.
2. solubility: low solubility in water, but in organic solvents (such as alcohol, ether) soluble.
3. melting point: melting point is about 212-216 ℃.
4. pH: form an acidic solution in water.
This compound is mainly used as a pharmaceutical intermediate and reagent, and the specific application is as follows:
1. Drug intermediates: used for the synthesis of anticancer drugs, antipsychotic drugs and antiepileptic drugs.
2. reagent: used for amination reaction and amine oxidation reaction in organic synthesis, and can be used as raw material of organic catalyst.
A common method for preparing 3-methyl-3-phenoxyazetidine hydrochloride is as follows:
3-Methyl-3-phenoxyazetidine was dissolved in alcohol and hydrochloric acid was added to react to precipitate the product as the hydrochloride salt. The pure 3-methyl-3-phenoxyazetidine hydrochloride was finally obtained by filtration, washing and drying.
Regarding safety information, 3-methyl-3-phenoxyazetidine hydrochloride is generally considered to be relatively safe under routine use. But the use should pay attention to the following matters:
1. Wear appropriate personal protective equipment, such as gloves and safety glasses.
2. avoid inhalation of dust, solution or vapor. In case of contact with skin or eyes, rinse with water for at least 15 minutes and seek medical help.
3. in the operation should ensure good ventilation, avoid odor accumulation.
4. storage should be sealed in a dry, cool place, away from the fire and oxidant.
1. Appearance: white crystalline solid.
2. solubility: low solubility in water, but in organic solvents (such as alcohol, ether) soluble.
3. melting point: melting point is about 212-216 ℃.
4. pH: form an acidic solution in water.
This compound is mainly used as a pharmaceutical intermediate and reagent, and the specific application is as follows:
1. Drug intermediates: used for the synthesis of anticancer drugs, antipsychotic drugs and antiepileptic drugs.
2. reagent: used for amination reaction and amine oxidation reaction in organic synthesis, and can be used as raw material of organic catalyst.
A common method for preparing 3-methyl-3-phenoxyazetidine hydrochloride is as follows:
3-Methyl-3-phenoxyazetidine was dissolved in alcohol and hydrochloric acid was added to react to precipitate the product as the hydrochloride salt. The pure 3-methyl-3-phenoxyazetidine hydrochloride was finally obtained by filtration, washing and drying.
Regarding safety information, 3-methyl-3-phenoxyazetidine hydrochloride is generally considered to be relatively safe under routine use. But the use should pay attention to the following matters:
1. Wear appropriate personal protective equipment, such as gloves and safety glasses.
2. avoid inhalation of dust, solution or vapor. In case of contact with skin or eyes, rinse with water for at least 15 minutes and seek medical help.
3. in the operation should ensure good ventilation, avoid odor accumulation.
4. storage should be sealed in a dry, cool place, away from the fire and oxidant.
Last Update：2024-04-09 21:21:28
