3-Methylpyrazin-2-Amine
2-Amino-3-methylpyrazine
CAS: 19838-08-5
Molecular Formula: C5H7N3
3-Methylpyrazin-2-Amine - Names and Identifiers
| Name | 2-Amino-3-methylpyrazine |
| Synonyms | (S)-HEXAHYDROPYRRO... 3-Methylpyrazin-2-Amine 3-methylpyrazin-2-amine 3-Methyl-2-pyrazinamine Pyrazinamine, 3-Methyl- 2-Amino-3-methylpyrazine 2-AMINO-3-METHYLPYRAZINE 2-Methyl-3-aMinopyrazine 2-Pyrazinamine,3-methyl- 3-Methylpyrazin-2-Ylamine 3-METHYLPYRAZIN-2-YLAMINE |
| CAS | 19838-08-5 |
| InChI | InChI=1/C5H7N3/c1-4-5(6)8-3-2-7-4/h2-3H,1H3,(H2,6,8) |
3-Methylpyrazin-2-Amine - Physico-chemical Properties
| Molecular Formula | C5H7N3 |
| Molar Mass | 109.13 |
| Density | 1.1118 (rough estimate) |
| Melting Point | 165-167 °C |
| Boling Point | 194.6°C (rough estimate) |
| Flash Point | 123.7°C |
| Vapor Presure | 0.0337mmHg at 25°C |
| Appearance | Solid |
| pKa | 3.56±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.5340 (estimate) |
| MDL | MFCD08705770 |
3-Methylpyrazin-2-Amine - Introduction
2-Amino-3-methylpyrazine, chemical formula C6H8N4, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2-Amino-3-methylpyrazine is a colorless to pale yellow crystal or crystalline powder.
-Solubility: Soluble in water, alcohols and organic solvents.
-Melting point: About 235-237 degrees Celsius.
Use:
-Pharmaceutical field: 2-Amino-3-methylpyrazine is widely used in drug synthesis, especially as an intermediate for antiviral drugs.
-Chemical reagent: can be used as dye and indicator.
Method:
There are many ways to prepare 2-Amino-3-methylpyrazine, one of the common methods is as follows:
-Reaction of benzamide and malononitrile under alkaline conditions to obtain aminopropionitrile.
-The aminopropionitrile is then reacted with acetone under the catalysis of acetic anhydride to produce 2-Amino-3-methylpyrazine.
Safety Information:
2-Amino-3-methylpyrazine is generally considered to be relatively safe under regular laboratory conditions, but the following safety precautions should be paid attention:
-Contact: Avoid skin contact. If contact occurs, rinse immediately with plenty of water.
-Inhalation: Avoid inhaling powders or aerosols. If you inhale them carelessly, move them to fresh air immediately.
-Consumption: 2-Amino-3-methylpyrazine should not be consumed.
-Storage: It should be stored in a dry, ventilated place, away from fire and oxidizing agents.
Please note that the above information is for reference only. The specific use of 2-amino-3-methylpyridine needs to be judged according to actual needs and experimental conditions, and should be carefully read and follow the relevant safety procedures before use.
Nature:
-Appearance: 2-Amino-3-methylpyrazine is a colorless to pale yellow crystal or crystalline powder.
-Solubility: Soluble in water, alcohols and organic solvents.
-Melting point: About 235-237 degrees Celsius.
Use:
-Pharmaceutical field: 2-Amino-3-methylpyrazine is widely used in drug synthesis, especially as an intermediate for antiviral drugs.
-Chemical reagent: can be used as dye and indicator.
Method:
There are many ways to prepare 2-Amino-3-methylpyrazine, one of the common methods is as follows:
-Reaction of benzamide and malononitrile under alkaline conditions to obtain aminopropionitrile.
-The aminopropionitrile is then reacted with acetone under the catalysis of acetic anhydride to produce 2-Amino-3-methylpyrazine.
Safety Information:
2-Amino-3-methylpyrazine is generally considered to be relatively safe under regular laboratory conditions, but the following safety precautions should be paid attention:
-Contact: Avoid skin contact. If contact occurs, rinse immediately with plenty of water.
-Inhalation: Avoid inhaling powders or aerosols. If you inhale them carelessly, move them to fresh air immediately.
-Consumption: 2-Amino-3-methylpyrazine should not be consumed.
-Storage: It should be stored in a dry, ventilated place, away from fire and oxidizing agents.
Please note that the above information is for reference only. The specific use of 2-amino-3-methylpyridine needs to be judged according to actual needs and experimental conditions, and should be carefully read and follow the relevant safety procedures before use.
Last Update：2024-04-09 15:17:54
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