3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid

3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid - Names and Identifiers

Name	3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid
Synonyms	RARECHEM AK HT T330 3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid 3-(BOC-AMINO)-3-(4-FLUOROPHENYL)PROPIONIC ACID 3-N-BOC-AMINO-3-(4-FLUOROPHENYL)PROPIONIC ACID 3-(Boc-amino)-3-(4-fluorophenyl)propionic acid 3-TERT-BUTOXYCARBONYLAMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID 3-(tert-Butoxycarbonylamino)-3-(4-fluorophenyl)propionic acid 3-[(tert-butoxycarbonyl)amino]-3-(4-fluorophenyl)propanoic acid 3-[(TERT-BUTOXYCARBONYL)AMINO]-3-(4-FLUOROPHENYL)PROPANOIC ACID 3-N-(TERT-BUTOXYCARBONYL)-AMINO-3-(4-FLUOROPHENYL)PROPIONIC ACID (3S)-3-[(tert-butoxycarbonyl)amino]-3-(4-fluorophenyl)propanoate (3R)-3-[(tert-butoxycarbonyl)amino]-3-(4-fluorophenyl)propanoate (3R)-3-(4-fluorophenyl)-3-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]propanoate
CAS	284493-72-7
EINECS	604-604-1
InChI	InChI=1/C14H18FNO4/c1-14(2,3)20-13(19)16-11(8-12(17)18)9-4-6-10(15)7-5-9/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)/p-1/t11-/m1/s1

3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid - Physico-chemical Properties

Molecular Formula	C14H18FNO4
Molar Mass	283.3
Density	1.1918 (estimate)
Melting Point	152-154°C (dec.)
Boling Point	424.5°C at 760 mmHg
Flash Point	210.5°C
Vapor Presure	5.8E-08mmHg at 25°C
Storage Condition	Sealed in dry,2-8°C
MDL	MFCD02090715

3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Hazard Class	IRRITANT

3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid - Introduction

3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid is an organic compound with the chemical formula C14H18FNO4.

Nature:
-Appearance: White solid
-Melting Point: about 110-115 ℃
-Solubility: Soluble in organic solvents such as ethanol, methanol and chloroform

Use:
3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid is an important intermediate commonly used in organic synthesis reactions. It can be used for drug synthesis, ligand synthesis, and modification of polypeptides and proteins in the field of medicine.

Method:
3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid is generally synthesized by the following steps:
1.4-fluorobenzoic acid is reacted with iminodimethanol ester to obtain 4-(carboxamido)-4-fluorobenzoic acid.
2.4-(carboxamido)-4-fluorobenzoic acid is reacted with N-protected amino propionate (such as Boc-amino) to generate 3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid.

Safety Information:
3-N-BOC-Amino-3-(4-fluorophenyl)propionicacid may be toxic to humans. Please use appropriate safety measures during operation, such as wearing gloves and protective glasses. At the same time, care should be taken to avoid contact with the skin or inhalation. For the specific toxicity and safety of the substance, please refer to the relevant literature or consult a professional.

Last Update：2024-04-09 21:11:58