3-N-Cbz-amino-2,6-dioxopiperidine - Names and Identifiers
Name | 3-N-Cbz-amino-2,6-dioxopiperidine
|
Synonyms | 3-Cbz-amino-2,6-dioxopiperidin 3-Cbz-amino-2,6-dioxopiperidine 3-N-Cbz-amino-2,6-dioxopiperidine benzyl 2,6-dioxopiperidin-3-ylcarbamate Benzyl (2,6-dioxopiperidin-3-yl)carbamate Carbamic acid, (2,6-dioxo-3-piperidinyl)-, phenylmethyl ester carbamic acid, N-(2,6-dioxo-3-piperidinyl)-, phenylmethyl ester Carbamic acid, (2,6-dioxo-3-piperidinyl)-, phenylmethyl ester (9CI)
|
CAS | 24666-55-5
|
InChI | InChI=1/C13H14N2O4/c16-11-7-6-10(12(17)15-11)14-13(18)19-8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,14,18)(H,15,16,17) |
3-N-Cbz-amino-2,6-dioxopiperidine - Physico-chemical Properties
Molecular Formula | C13H14N2O4
|
Molar Mass | 262.26 |
Density | 1.31±0.1 g/cm3(Predicted) |
Melting Point | 129-131 °C(Solv: isopropanol (67-63-0)) |
Boling Point | 520.2±49.0 °C(Predicted) |
Flash Point | 268.4°C |
Vapor Presure | 6.37E-11mmHg at 25°C |
pKa | 10.58±0.20(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.58 |
3-N-Cbz-amino-2,6-dioxopiperidine - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
HS Code | 29333990 |
3-N-Cbz-amino-2,6-dioxopiperidine - Introduction
3-N-Cbz-amino-2,6-dioxopiperidine(3-N-Cbz-amino-2,6-dioxopiperidine) is an organic compound with the chemical formula C13H14N2O4.
In terms of properties, 3-N-Cbz-amino-2,6-dioxopiperidine is a white to pale yellow solid with a specific molecular structure. It can be dissolved in organic solvents such as ethanol, dimethyl sulfoxide and chloroform.
In terms of application, 3-N-Cbz-amino-2,6-dioxopiperidine is often used as an intermediate in organic synthesis. It can be used to synthesize various compounds containing piperidine structure, such as anticancer drugs and antiviral drugs.
The preparation method of this compound is generally through the reaction of carboxylic acid and the corresponding amine to generate amide, and then the carbinol ring reaction of the amide to obtain 3-N-Cbz-amino-2,6-dioxopiperidine.
When using and handling this compound, attention should be paid to safety. 3-N-Cbz-amino-2,6-dioxopiperidine may be irritating to the eyes, skin, and respiratory tract, so use appropriate protective equipment to avoid contact with skin and eyes. In addition, it should be operated in a well-ventilated place and away from fire and high temperature. When dealing with waste, it should be handled and disposed of in accordance with local regulations.
Last Update:2024-04-10 22:30:50