3-Oxo-3-(4-pyridyl)propanenitrile

3-Oxo-3-(4-pyridyl)propanenitrile - Names and Identifiers

Name	3-Oxo-3-(4-pyridinyl)propanenitrile
Synonyms	4-(2-Cyanoacetyl)pyridine 4-pyridinepropanenitrile, β-oxo- 4-Pyridinepropanenitrile, β-oxo- 3-Oxo-3-(4-pyridyl)propanenitrile Beta-oxo-4-pyridinepropanenitrile 3-OXO-3-PYRIDIN-4-YL-PROPIONITRILE 3-OXO-3-PYRIDIN-4-YLPROPANENITRILE 3-OXO-4-PYRIDIN-3-YL-PROPIONITRILE 3-Oxo-3-(4-pyridinyl)propanenitrile 3-oxo-3-(pridine-4-yl)propanenitrile 3-oxo-3-(pyridin-4-yl)propanenitrile
CAS	23821-37-6
InChI	InChI=1/C8H6N2O/c9-4-1-8(11)7-2-5-10-6-3-7/h2-3,5-6H,1H2

3-Oxo-3-(4-pyridyl)propanenitrile - Physico-chemical Properties

Molecular Formula	C8H6N2O
Molar Mass	146.15
Density	1.177±0.06 g/cm3(Predicted)
Boling Point	335.3±22.0 °C(Predicted)
Flash Point	156.6°C
Vapor Presure	0.000121mmHg at 25°C
pKa	6.29±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.539

3-Oxo-3-(4-pyridyl)propanenitrile - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.

3-Oxo-3-(4-pyridyl)propanenitrile - Introduction

3-Oxo-3-(4-pyridinyl)propanenitrile is an organic compound with the chemical formula C10H8N2O. It is a colorless to light yellow solid, with good solubility, soluble in water and organic solvents.

3-Oxo-3-(4-pyridinyl)propanenitrile has certain applications in the field of organic synthesis. It can be used as an intermediate in the synthesis of other organic compounds, such as active ingredients in pharmaceuticals and pesticides, dyes and photosensitizers.

There are various methods for preparing 3-Oxo-3-(4-pyridinyl)propanenitrile, the most common method is the intramolecular condensation of 4-pyridinecarboxaldehyde with hydrocyanic acid to give 3-imino-3-(4-pyridyl) propionitrile, followed by dehydration oxidation to give the target product.

Regarding safety information, 3-Oxo-3-(4-pyridinyl)propanenitrile is less toxic under general operating conditions, but it is still necessary to follow laboratory safety procedures, such as wearing protective gloves, glasses and lab coats, etc. Also, avoid inhalation or contact with skin. If accidental contact, rinse immediately with clean water and seek medical help.

Last Update：2024-04-09 20:52:54