3-PEHPC
NE 10790
CAS: 152831-36-2
Molecular Formula: C8H10NO6P
3-PEHPC - Names and Identifiers
| Name | NE 10790 |
| Synonyms | 3-PEHPC NE 10790 NE 10790 (3-PEHPC) FJVYPXVLXQXDHM-UHFFFAOYSA-N 3-Pyridinepropanoic acid, α-hydroxy-α-phosphono- 2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoic acid |
| CAS | 152831-36-2 |
3-PEHPC - Physico-chemical Properties
| Molecular Formula | C8H10NO6P |
| Molar Mass | 247.14 |
| Density | 1.724±0.06 g/cm3(Predicted) |
| Boling Point | 583.6±60.0 °C(Predicted) |
| pKa | 1.73±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Use | NE 10790 is a weak inhibitor of farni pyrophosphate (FPP) synthetase, a potent phosphate analog of bisphosphate, and a weak anti-absorbent. |
| In vitro study | NE 10790 inhibits incorporation of [ 14 C]mevalonic acid into Rab6, but not into H-Ras or Rap1, proteins that are modified by FTase and GGTase I, respectively. NE 10790 reduces viability in J774 cells. NE 10790 prevents prenylation of 22-26-kDa proteins that are not modified by FTase or GGTase I. |
3-PEHPC - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 4.046 ml | 20.231 ml | 40.463 ml |
| 5 mM | 0.809 ml | 4.046 ml | 8.093 ml |
| 10 mM | 0.405 ml | 2.023 ml | 4.046 ml |
| 5 mM | 0.081 ml | 0.405 ml | 0.809 ml |
Last Update：2024-01-02 23:10:35
3-PEHPC - Reference Information
| biological activity | NE 10790 is a weak inhibitor of farnesyl pyrophosphate (FPP) synthetase, it is a potent phosphate analog of lixet diphosphate and is also a weak anti-absorbent. |
| Target | FPP synthase. |
Last Update：2024-04-09 20:52:54
