3-PyridinaMine,5-broMo-2-Methoxy-
5-bromo-2-methoxy-pyridin-3-amine
CAS: 884495-39-0
Molecular Formula: C6H7BrN2O
3-PyridinaMine,5-broMo-2-Methoxy- - Names and Identifiers
3-PyridinaMine,5-broMo-2-Methoxy- - Physico-chemical Properties
| Molecular Formula | C6H7BrN2O |
| Molar Mass | 203.04 |
| Density | 1.622±0.06 g/cm3(Predicted) |
| Melting Point | 53-55℃ |
| Boling Point | 284.5±35.0 °C(Predicted) |
| Flash Point | 125.9°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.00296mmHg at 25°C |
| pKa | 1.98±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.602 |
| MDL | MFCD07368887 |
3-PyridinaMine,5-broMo-2-Methoxy- - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
3-PyridinaMine,5-broMo-2-Methoxy- - Reference Information
| introduction | 3-amino -5-bromo -2-methoxypyridine is a light green solid and slightly soluble in water. 3-Amino-5-bromo-2-methoxypyridine is a pyridine derivative with a certain alkalinity. It can be used as a denaturant, dye aid, and synthesis of a series of products (including drugs, Disinfectants, dyes, etc.). |
| use | 3-amino -5-bromo -2-methoxypyridine can be used as a pharmaceutical intermediate, a synthetic intermediate for coatings. In the synthetic transformation, it mainly revolves around the bromine atom and amino group on the pyridine ring. The common transformation is to convert the bromine atom into boric acid or borate; the amino group is converted into halogen atom through diazotization. |
| synthesis method | combine 5-bromo-2-methoxy-3-nitropyridine (5.0g, 21.55 mmol) and tin chloride (II) dihydrate (24.35g, dissolve the mixture 107.75 mmol) into ethyl acetate (0.2 L), stir the mixture at 50°C for 3 hours under nitrogen atmosphere, dilute the mixture with EtOAc (0.8 L), wash the mixture twice with 1 N sodium hydroxide (1.2 L) and water, dry the mixture with magnesium sulfate, filter to remove magnesium sulfate solid precipitate, the resulting filtrate was concentrated to obtain 3-amino-5-bromo-2-methoxypyridine. Figure 13-Amino-5-bromo-2-methoxypyridine synthesis route |
Last Update：2024-04-09 21:04:16
Supplier List
Product Name: 3-Amino-5-Bromo-2-Methoxypyridine Visit Supplier Webpage Request for quotation
CAS: 884495-39-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 884495-39-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: 3-Amino-5-Bromo-2-Methoxypyridine Visit Supplier Webpage Request for quotation
CAS: 884495-39-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 884495-39-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History