3-Pyridinecarbonitrile, 2-chloro-5-fluoro-

3-Pyridinecarbonitrile, 2-chloro-5-fluoro- - Names and Identifiers

Name	2-Chloro-5-fluoronicotinonitrile
Synonyms	2-Chloro-5-fluoronicotinonitrile 2-Chloro-5-fluoropyridine-3-carbonitrile 2-Chloro-5-fluoro-3-pyridinecarbonitrile 3-Pyridinecarbonitrile, 2-chloro-5-fluoro-
CAS	791644-48-9

3-Pyridinecarbonitrile, 2-chloro-5-fluoro- - Physico-chemical Properties

Molecular Formula	C6H2ClFN2
Molar Mass	156.54
Density	1.43
Boling Point	235℃
Flash Point	96℃
pKa	-4.51±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

3-Pyridinecarbonitrile, 2-chloro-5-fluoro- - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

3-Pyridinecarbonitrile, 2-chloro-5-fluoro- - Upstream Downstream Industry

Raw Materials

2,4-Pentadienoic acid, 2-cyano-5-(dimethylamino)-4-fluoro-, ethyl ester, (2E,4Z)-
2-CHLORO-5-FLUORO-3-PYRIDINECARBONYL CHLORIDE
2-Chloro-5-fluoronicotinic acid
2-chloro-5-fluoronicotinaMide
2,6-Dichloro-5-fluoronicotinic acid
2-CHLORO-5-FLUORO-3-IODOPYRIDINE
Ethyl 2-chloro-5-fluoronicotinate
2-CHLORO-5-FLUORO-PYRIDINE-3-CARBALDEHYDE
2,6-DICHLORO-5-FLUORONICOTINAMIDE
2,6-Dichloro-5-fluoro-3-pyridinecarbonitrile

3-Pyridinecarbonitrile, 2-chloro-5-fluoro- - Introduction

Is an organic compound with the chemical formula C6H2ClFN2. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White solid or crystalline.
-Melting point: about 82-86 ° C.
-Boiling point: About 238-244 ° C.
-Solubility: Soluble in organic solvents, such as ethanol, ether.

Use:
-Chemical intermediates: As an important intermediate in organic synthesis, it can be used in the synthesis of various drugs and pesticides.
-Pesticides: Its derivatives are often used as pesticides for agricultural protection.

Method:
Synthesis can generally be achieved through the following steps:
1. 2-Chloro-5-fluoropyridine reacts with sodium cyanide in alcohol.
2. The product was obtained by filtration and then purified by crystallization.

Safety Information:
-is an organic compound and should be handled in strict accordance with laboratory safety procedures.
-Avoid contact with skin, eyes and respiratory tract. Wear protective gloves, goggles and protective masks.
-Avoid inhaling its vapors and maintain good ventilation during operation.
-If ingested by mistake or inhaled, consult a doctor immediately and show the container or label to the doctor.
-Waste disposal: Local regulations should be followed and do not dump into water bodies or the environment.

Last Update：2024-04-09 02:00:51