3-amino-6-bromo-pyrazine-2-carboxamide

3-amino-6-bromo-pyrazine-2-carboxamide - Names and Identifiers

Name	3-amino-6-bromo-pyrazine-2-carboxamide
Synonyms	3-Amino-6-bromo-2-pyrazinecarboxamide 3-Amino-6-bromopyrazine-2-carboxamide 3-amino-6-bromo-pyrazine-2-carboxamide 2-Pyrazinecarboxamide, 3-amino-6-bromo- 2-pyrazinecarboxamide, 3-amino-6-bromo-
CAS	17890-77-6
InChI	InChI=1/C5H5BrN4O/c6-2-1-9-4(7)3(10-2)5(8)11/h1H,(H2,7,9)(H2,8,11)

3-amino-6-bromo-pyrazine-2-carboxamide - Physico-chemical Properties

Molecular Formula	C5H5BrN4O
Molar Mass	217.02
Density	1.919
Melting Point	215-217 °C
Boling Point	333.8±42.0 °C(Predicted)
Flash Point	155.657°C
Vapor Presure	0mmHg at 25°C
Appearance	powder to crystal
Color	White to Orange to Green
pKa	13.06±0.50(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	Irritant
Refractive Index	1.692
MDL	MFCD13689185

3-amino-6-bromo-pyrazine-2-carboxamide - Introduction

It is a compound whose molecular formula is C9H8BrN5O.

Nature:
-Appearance: White crystalline powder.
-Solubility: Soluble in some organic solvents, such as ethanol, chloroform and dichloromethane.
-Melting point: About 181-183 ° C.

Use:
Many important applications in the field of medicine include:
-Anti-tumor drug: It can be used as a synthetic intermediate for the synthesis of a variety of anti-cancer drugs.
-Gene transduction research: It can also be used for gene transduction and protein-nucleic acid interaction research.

Method:
The preparation method includes the following steps:
1. 3-Amino-6-bromopyrazine was coupled with formic acid in chloroform.
2. Obtain by crystallization and vacuum drying.

Safety Information:
The following safety precautions should be observed during use:
-It is an organic compound that may be irritating to the skin and eyes, so wear appropriate protective equipment during operation.
-Avoid inhaling the vapors of its powder or solution.
-Must operate in a well-ventilated laboratory and keep the laboratory environment clean.
-During storage and handling, avoid contact with oxidants and strong acids to avoid dangerous chemical reactions.

Please note that safe procedures must be followed when using chemical reagents, and relevant safety data sheets and laboratory instructions must always be read and followed. For specific chemical reagents, it is best to refer to the relevant literature or consult a professional for detailed information.

Last Update：2024-04-09 21:32:38