3-ammonio-3-(5-methyl-2-furyl)propanoate
3-Amino-3-(5-methyl-2-furyl)propanoic acid
CAS: 439121-19-4
Molecular Formula: C8H11NO3
3-ammonio-3-(5-methyl-2-furyl)propanoate - Names and Identifiers
3-ammonio-3-(5-methyl-2-furyl)propanoate - Physico-chemical Properties
| Molecular Formula | C8H11NO3 |
| Molar Mass | 169.18 |
| Density | 1.235±0.06 g/cm3(Predicted) |
| Melting Point | 207-209 °C (decomp) |
| Boling Point | 265.9±40.0 °C(Predicted) |
| pKa | 3.37±0.12(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD02661897 |
3-ammonio-3-(5-methyl-2-furyl)propanoate - Introduction
3-Amino-3-(5-methyl-2-furyl)propanoic acid, chemical formula C8H11NO3, is an organic compound.
Nature:
-Appearance: white solid powder
-Density: approx. 1.23g/cm³
-Melting point: approx. 125-128°C
-Solubility: The solubility in water is better, and the solubility increases with the increase of temperature.
Use:
3-Amino-3-(5-methyl-2-furyl)propanoic acid has a variety of uses, including:
-As an intermediate in drug synthesis, used to prepare some pharmaceuticals and bioactive molecules.
-As a raw material for food additives, used in the production of flavoring agents and food preservatives.
-used in the laboratory as a dye, labeling agent, amino acid analysis reagent.
Preparation Method:
Generally, 3-Amino-3-(5-methyl-2-furyl)propanoic acid can be synthesized by the following steps:
1.5-methyl furan -2-carbaldehyde is reacted with methyl ring amine to generate N-methyl -5-methyl furan -2-methyl amine.
2. N-methyl-5-methylfuran-2-methylamine is reacted with methyl succinate to produce N-methyl-3-(5-methylfuran-2-yl) malonimide.
3. Finally, N-methyl -3-(5-methylfuran-2-yl) malonimide is reacted with ammonia water to generate 3-Amino-3-(5-methyl-2-furyl)propanoic acid.
Safety Information:
There are few detailed reports on the toxicity and danger of 3-Amino-3-(5-methyll-2-furyl) propanoic acid, but in general, the following safety measures should be noted:
-Avoid direct contact with skin and eyes as it may cause irritation.
-Pay attention to protective measures during use, handling and storage, such as wearing chemical protective gloves, safety glasses and protective clothing.
-It should be used in a well-ventilated place to avoid inhaling dust or vapor.
-If no special requirements, should be stored in a cool, dry place, away from the fire and flammable materials.
Nature:
-Appearance: white solid powder
-Density: approx. 1.23g/cm³
-Melting point: approx. 125-128°C
-Solubility: The solubility in water is better, and the solubility increases with the increase of temperature.
Use:
3-Amino-3-(5-methyl-2-furyl)propanoic acid has a variety of uses, including:
-As an intermediate in drug synthesis, used to prepare some pharmaceuticals and bioactive molecules.
-As a raw material for food additives, used in the production of flavoring agents and food preservatives.
-used in the laboratory as a dye, labeling agent, amino acid analysis reagent.
Preparation Method:
Generally, 3-Amino-3-(5-methyl-2-furyl)propanoic acid can be synthesized by the following steps:
1.5-methyl furan -2-carbaldehyde is reacted with methyl ring amine to generate N-methyl -5-methyl furan -2-methyl amine.
2. N-methyl-5-methylfuran-2-methylamine is reacted with methyl succinate to produce N-methyl-3-(5-methylfuran-2-yl) malonimide.
3. Finally, N-methyl -3-(5-methylfuran-2-yl) malonimide is reacted with ammonia water to generate 3-Amino-3-(5-methyl-2-furyl)propanoic acid.
Safety Information:
There are few detailed reports on the toxicity and danger of 3-Amino-3-(5-methyll-2-furyl) propanoic acid, but in general, the following safety measures should be noted:
-Avoid direct contact with skin and eyes as it may cause irritation.
-Pay attention to protective measures during use, handling and storage, such as wearing chemical protective gloves, safety glasses and protective clothing.
-It should be used in a well-ventilated place to avoid inhaling dust or vapor.
-If no special requirements, should be stored in a cool, dry place, away from the fire and flammable materials.
Last Update：2024-04-09 21:54:55
