3-bromo-2-(chloromethyl)pyridine
3-bromo-2-(chloromethyl)pyridine
CAS: 122851-69-8
Molecular Formula: C6H5BrClN
3-bromo-2-(chloromethyl)pyridine - Names and Identifiers
| Name | 3-bromo-2-(chloromethyl)pyridine |
| Synonyms | 3-bromo-2-(chloromethyl)pyridine Pyridine, 3-bromo-2-(chloromethyl)- |
| CAS | 122851-69-8 |
3-bromo-2-(chloromethyl)pyridine - Physico-chemical Properties
| Molecular Formula | C6H5BrClN |
| Molar Mass | 206.47 |
| Density | 1.631±0.06 g/cm3(Predicted) |
| Melting Point | 46-46.5 °C(Solv: hexane (110-54-3); ethyl ether (60-29-7)) |
| Boling Point | 237.9±25.0 °C(Predicted) |
| pKa | 1.35±0.22(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
3-bromo-2-(chloromethyl)pyridine - Risk and Safety
| Hazard Class | IRRITANT |
3-bromo-2-(chloromethyl)pyridine - Upstream Downstream Industry
| Raw Materials | (3-bromopyridin-2-yl)methanol |
3-bromo-2-(chloromethyl)pyridine - Introduction
3-bromo-2-(chlorine) pyridine is an organic compound with the chemical formula C6H5BrClN. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 3-bromo-2-(chlorine) pyridine is a colorless to yellow solid.
-Melting point: Its melting point range is about 80-85 ° C.
-Solubility: The compound is soluble in many organic solvents, such as dimethyl sulfoxide, acetonitrile and dimethylformamide.
Use:
-Chemical synthesis: 3-bromo-2-(chloromethyl)pyridine can be used as an intermediate in organic synthesis for the synthesis of various organic compounds.
-Pharmaceutical research: It is also often used as a starting material for organic synthesis in the field of pharmaceutical research.
Method:
The synthesis of -3-bromo-2-(chloromethyl)pyridine is usually obtained by reacting 3-bromopyridine with methyl chloride. The reaction conditions can be optimized according to the specific experimental design and requirements.
Safety Information:
- 3-bromo-2-(chloromethyl)pyridine may be harmful to the human body, so appropriate protective measures should be taken when using it, such as wearing protective glasses and gloves.
-During storage and handling, care should be taken to avoid contact with oxidants, strong acids and strong bases to avoid toxic gases.
-The compound should be stored in a closed container and stored in a cool, dry place.
Nature:
-Appearance: 3-bromo-2-(chlorine) pyridine is a colorless to yellow solid.
-Melting point: Its melting point range is about 80-85 ° C.
-Solubility: The compound is soluble in many organic solvents, such as dimethyl sulfoxide, acetonitrile and dimethylformamide.
Use:
-Chemical synthesis: 3-bromo-2-(chloromethyl)pyridine can be used as an intermediate in organic synthesis for the synthesis of various organic compounds.
-Pharmaceutical research: It is also often used as a starting material for organic synthesis in the field of pharmaceutical research.
Method:
The synthesis of -3-bromo-2-(chloromethyl)pyridine is usually obtained by reacting 3-bromopyridine with methyl chloride. The reaction conditions can be optimized according to the specific experimental design and requirements.
Safety Information:
- 3-bromo-2-(chloromethyl)pyridine may be harmful to the human body, so appropriate protective measures should be taken when using it, such as wearing protective glasses and gloves.
-During storage and handling, care should be taken to avoid contact with oxidants, strong acids and strong bases to avoid toxic gases.
-The compound should be stored in a closed container and stored in a cool, dry place.
Last Update：2024-04-09 20:49:11
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CAS: 122851-69-8
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QQ: 3008007409
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CAS: 122851-69-8
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Raw Materials for 3-bromo-2-(chloromethyl)pyridine