3-bromo-5-(1,1-dimethylethyl)-4,5-dihydro-Isoxazole
3-Bromo-5-tert-butyl-4,5-dihydroisoxazole
CAS: 128464-85-7
Molecular Formula: C7H12BrNO
3-bromo-5-(1,1-dimethylethyl)-4,5-dihydro-Isoxazole - Names and Identifiers
3-bromo-5-(1,1-dimethylethyl)-4,5-dihydro-Isoxazole - Physico-chemical Properties
| Molecular Formula | C7H12BrNO |
| Molar Mass | 206.08 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD11707001 |
3-bromo-5-(1,1-dimethylethyl)-4,5-dihydro-Isoxazole - Introduction
3-Bromo-5-tert-butyl-4,5-dihydroisoxazole(3-Bromo-5-tert-butyl-4,5-dihydroisoxazole) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless liquid or white solid.
-Molecular formula: C8H14BrNO.
-Molecular weight: 213.11g/mol.
-Melting point: about 25-26°C.
-Boiling point: about 103-105 ℃.
-Solubility: Soluble in alcohol, ether and organic solvents.
Use:
- 3-Bromo-5-tert-butyl-4,5-dihydroisoxazole is commonly used as an intermediate in organic synthesis. It can participate in a variety of chemical reactions, such as cyclization reaction, substitution reaction and coupling reaction.
-This compound is also used in the synthesis of pesticides, pharmaceuticals and fungicides.
Preparation Method:
The synthesis of -3-Bromo-5-tert-butyl-4,5-dihydroisoxazole is usually carried out by the following steps:
1. Oxidation of isoxazole to the corresponding isoxazole oxide;
2. electrophilic substitution reaction of isoxazole oxide, using cuprous bromide and other reagents to introduce bromine group;
3. The use of tert-butanol and base-catalyzed condensation reaction, the target product.
Safety Information:
- 3-Bromo-5-tert-butyl-4,5-dihydroisoxazole is irritating and toxic, and attention should be paid to safe operation.
-During the operation, appropriate personal protective measures should be taken, such as wearing protective glasses, gloves and laboratory coats.
-Avoid contact with skin and inhalation of vapors. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-This compound should be stored in a sealed container, away from fire and oxidizing agents.
Nature:
-Appearance: Colorless liquid or white solid.
-Molecular formula: C8H14BrNO.
-Molecular weight: 213.11g/mol.
-Melting point: about 25-26°C.
-Boiling point: about 103-105 ℃.
-Solubility: Soluble in alcohol, ether and organic solvents.
Use:
- 3-Bromo-5-tert-butyl-4,5-dihydroisoxazole is commonly used as an intermediate in organic synthesis. It can participate in a variety of chemical reactions, such as cyclization reaction, substitution reaction and coupling reaction.
-This compound is also used in the synthesis of pesticides, pharmaceuticals and fungicides.
Preparation Method:
The synthesis of -3-Bromo-5-tert-butyl-4,5-dihydroisoxazole is usually carried out by the following steps:
1. Oxidation of isoxazole to the corresponding isoxazole oxide;
2. electrophilic substitution reaction of isoxazole oxide, using cuprous bromide and other reagents to introduce bromine group;
3. The use of tert-butanol and base-catalyzed condensation reaction, the target product.
Safety Information:
- 3-Bromo-5-tert-butyl-4,5-dihydroisoxazole is irritating and toxic, and attention should be paid to safe operation.
-During the operation, appropriate personal protective measures should be taken, such as wearing protective glasses, gloves and laboratory coats.
-Avoid contact with skin and inhalation of vapors. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-This compound should be stored in a sealed container, away from fire and oxidizing agents.
Last Update：2024-04-09 15:18:09
