Name | 3-bromo-7-nitro-2H-indazole |
Synonyms | BRNI 3-Bromo-7-nitroindaz 3-BROMO-7-NITROINDAZOLE 7-NITROINDAZOLE, 3-BROMO- 3-bromo-7-iodo-2H-indazole 3-bromo-7-nitro-2H-indazole 3-BROMO-7-NITRO-1H-INDAZOLE 3-Bromo-7-nitro-1H-indazole 3-BroMo-7-nitro-1H-indazo... 1H-INDAZOLE,3-BROMO-7-NITRO- 1H-Indazole, 3-bromo-7-nitro- |
CAS | 74209-34-0 945761-95-5 |
InChI | InChI=1/C7H4BrIN2/c8-7-4-2-1-3-5(9)6(4)10-11-7/h1-3H,(H,10,11) |
Molecular Formula | C7H4BrN3O2 |
Molar Mass | 242.03 |
Density | 1.8856 (rough estimate) |
Melting Point | 175-185 °C |
Boling Point | 182°C |
Flash Point | 100.7°C |
Solubility | ethanol: 25mg/mL |
Vapor Presure | 0.033mmHg at 25°C |
Appearance | powder |
Color | light yellow |
pKa | 7.85±0.40(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Sensitive | Light Sensitive |
Refractive Index | 1.6200 (estimate) |
Hazard Symbols | T - Toxic |
Risk Codes | 60 - May impair fertility |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
WGK Germany | 3 |
Hazard Note | Harmful to reproduction |
Hazard Class | IRRITANT |
Biological activity | 3-Bromo-7-nitroindazole is an effective, selective neuronal nitric oxide synthase (nNOS) inhibitor, compared with eNOS or inducible nitric oxide synthase (iNOS), its effect is stronger. 3-Bromo-7-nitroindazole affects the synthesis of intercellular messenger nitric oxide (NO) throughout the body and brain. |
target | nNOS |