3-bromopyridin-2(1H)-one
3-Bromo-2-hydroxypyridine
CAS: 13466-43-8
Molecular Formula: C5H4BrNO
3-bromopyridin-2(1H)-one - Names and Identifiers
3-bromopyridin-2(1H)-one - Physico-chemical Properties
| Molecular Formula | C5H4BrNO |
| Molar Mass | 174 |
| Density | 1.776±0.06 g/cm3(Predicted) |
| Melting Point | 179-183 °C |
| Boling Point | 336.6±42.0 °C(Predicted) |
| Flash Point | 157.4°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.000111mmHg at 25°C |
| Appearance | Bright light brown crystalline powder |
| Color | White to off-white |
| BRN | 109846 |
| pKa | 10.53±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.6 |
| MDL | MFCD03411569 |
3-bromopyridin-2(1H)-one - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| HS Code | 29337900 |
3-bromopyridin-2(1H)-one - Introduction
3-Bromo-2-hydroxypyridine is an organic compound with the chemical formula C5H4BrNO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. Appearance: 3-bromo-2-hydroxypyridine is a colorless to pale yellow solid.
2. Solubility: Soluble in most organic solvents, such as ethanol, chloroform and dimethylformamide.
3. melting point: about 70-75 degrees Celsius.
4. Stability: relatively stable at room temperature, but may react when encountering strong oxidants.
Use:
1. chemical synthesis: 3-bromo -2-hydroxyl pyridine can be used as a synthetic intermediate of some organic compounds.
2. Drug research: The compound is widely used in the field of drug research, such as the synthesis of antibacterial and antiviral drugs.
3. other applications: can also be used in dyes, coatings and pesticides and other fields.
Preparation Method:
3-Bromo-2-hydroxypyridine can usually be prepared by the following steps:
1.3-Bromopyridine reacts with an alkaline solution to generate 3-bromo -2-pyridone.
2.3-bromo -2-pyridone is reacted with aldehyde or ketone to generate target product 3-bromo -2-hydroxyl pyridine.
Safety Information:
1. 3-Bromo-2-hydroxypyridine is an organic solvent. Prolonged contact with skin should be avoided, which can cause irritation and sensitive reactions.
2. Wear appropriate protective equipment during operation, including gloves, safety goggles and protective clothing.
3. storage should be away from the fire and oxidant, avoid high temperature and open fire.
4. In case of inadvertent contact or inhalation, wash the area immediately and seek medical attention.
Please note that for more detailed information about this compound and the safety requirements for specific applications, please refer to relevant literature or consult with professional organizations.
Nature:
1. Appearance: 3-bromo-2-hydroxypyridine is a colorless to pale yellow solid.
2. Solubility: Soluble in most organic solvents, such as ethanol, chloroform and dimethylformamide.
3. melting point: about 70-75 degrees Celsius.
4. Stability: relatively stable at room temperature, but may react when encountering strong oxidants.
Use:
1. chemical synthesis: 3-bromo -2-hydroxyl pyridine can be used as a synthetic intermediate of some organic compounds.
2. Drug research: The compound is widely used in the field of drug research, such as the synthesis of antibacterial and antiviral drugs.
3. other applications: can also be used in dyes, coatings and pesticides and other fields.
Preparation Method:
3-Bromo-2-hydroxypyridine can usually be prepared by the following steps:
1.3-Bromopyridine reacts with an alkaline solution to generate 3-bromo -2-pyridone.
2.3-bromo -2-pyridone is reacted with aldehyde or ketone to generate target product 3-bromo -2-hydroxyl pyridine.
Safety Information:
1. 3-Bromo-2-hydroxypyridine is an organic solvent. Prolonged contact with skin should be avoided, which can cause irritation and sensitive reactions.
2. Wear appropriate protective equipment during operation, including gloves, safety goggles and protective clothing.
3. storage should be away from the fire and oxidant, avoid high temperature and open fire.
4. In case of inadvertent contact or inhalation, wash the area immediately and seek medical attention.
Please note that for more detailed information about this compound and the safety requirements for specific applications, please refer to relevant literature or consult with professional organizations.
Last Update：2024-04-09 15:17:51
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Product Name: Lasmiditan Impurity 40 Visit Supplier Webpage Request for quotationCAS: 13466-43-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: 3-Bromo-2-hydroxypyridine Visit Supplier Webpage Request for quotationCAS: 13466-43-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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