3-carbethoxy-4-hydroxy-2-quinolone

3-carbethoxy-4-hydroxy-2-quinolone - Names and Identifiers

Name	1,2-DIHYDRO-4-HYDROXY-2-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER
Synonyms	AURORA KA-4464 3-carbethoxy-4-hydroxy-2-quinolone 3-Ethoxycarbonyl-2,4-dihydroxyquinoline ethyl 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate Ethyl 4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxylate 1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxylicaciethylester 1,2-DIHYDRO-4-HYDROXY-2-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER 4-HYDROXY-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS	40059-53-8

3-carbethoxy-4-hydroxy-2-quinolone - Physico-chemical Properties

Molecular Formula	C12H11NO4
Molar Mass	233.22
Density	1.378±0.06 g/cm3(Predicted)
Melting Point	208 °C
Boling Point	458.0±45.0 °C(Predicted)
pKa	4.50±1.00(Predicted)
Storage Condition	Sealed in dry,Room Temperature

3-carbethoxy-4-hydroxy-2-quinolone - Upstream Downstream Industry

Raw Materials

Benzoic acid, 2-[(3-ethoxy-1,3-dioxopropyl)amino]-, ethyl ester
Propanedioic acid, 2-[hydroxy(2-nitrophenyl)methylene]-, 1,3-diethyl ester
Propanedioic acid, 2-[[2-[(ethoxycarbonyl)amino]phenyl]hydroxymethylene]-, 1,3-diethyl ester
Triethyl methanetricarboxylate
2-METHYL-3,1-BENZOXAZA-4-ONE
3-Quinolinecarboxylic acid, 1-ethyl-1,2-dihydro-4-hydroxy-2-oxo-, ethyl ester
ETHYL ANTHRANILATE
Diethyl malonate
Sodium ethoxide
Ethyl acetate
Aniline
Isatoic Anhydride
Methyl anthranilate

Downstream Products

4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID

3-carbethoxy-4-hydroxy-2-quinolone - Introduction

ACID ETHYL ESTER is a chemical compound also known as 1,2-dihydro-4-hydroxy-2-keto-3-quinolinecarboxylic ACID ETHYL ESTER. The following is a description of the properties, uses, preparation methods and safety information of the compound:

Nature:
-Appearance: 1, ACID ETHYL ESTER is yellow crystal or powder.
-Molecular formula: C11H9NO4
-Molecular weight: 223.19g/mol
-Melting Point: about 110-112 ° C
-Boiling point: About 370 ° C

Use:
- 1, acethyl ESTER is a drug intermediate commonly used in the synthesis of antibiotics, antiviral drugs and anti-cancer drugs and other drug compounds.
-It can also be used as a photosensitizer, dye and raw material for organic synthesis.

Method:
1. The preparation of ACID ETHYL ESTER can be carried out by the following steps:
1. The amino ketone reacts with formic acid and sulfuric acid to generate 2-hydroxyquinoline -3-carboxylic acid.
2. In anhydrous ether, it reacts with acid chloride to generate 2,4-dihydroxyquinoline -3-carboxylic acid ethyl acetate.
3. Finally, the product is reacted with ethanol to obtain 1, ACID ETHYL ESTER.

Safety Information:
- 1, ACID ETHYL ESTER has certain toxicity and needs to be handled carefully.
-Avoid contact with oxidants, strong bases and strong acids during use or storage.
-Use with suitable protective gloves, glasses and a protective mask to avoid direct contact with skin, eyes and respiratory tract. During operation, good ventilation should be maintained.
-Safety practices should be followed when handling and storing the substance. If you are accidentally poisoned or exposed, you should seek medical attention immediately.

Last Update：2024-04-09 21:00:56